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Latest from City of Hope


Expert Explains Role for Newly Approved TKI/mTOR Combo in RCC

May 25, 2016

Sumanta Kumar Pal, MD, provides insight on the FDA approval of the TKI lenvatinib in combination with everolimus, an mTOR inhibitor as a treatment for patients with advanced RCC following prior antiangiogenic therapy.

Reason Versus Dogma: It's Time to Move Beyond the Phase III Trial Mantra

May 19, 2016

Shouldn’t the goal of oncologists be to do what is best for their patients, regardless of the currently existing level of evidence and particularly when any timeline for obtaining that "gold standard" evidence will be irrelevant for the patient being cared for today?

Germline Genetic Testing Raises Thorny Ethical Questions

May 03, 2016

If germline testing for a cancer-associated purpose reveals the risk of an unrelated illness like Alzheimer disease, should patients routinely be told—even if there’s nothing that can be done about that “incidental” finding?

City of Hope Conference for Clinicians Will Teach Best Practices in Blood Cancers

January 12, 2016

City of Hope is offering an interactive educational conference for oncologists, hematologists and oncology nurses to learn about the latest advances in bone marrow transplants, as well as the treatment of leukemia, lymphoma and myeloma.

It's Time for True Advances in Comparative Effectiveness Research

December 21, 2015

It is simply unrealistic and highly counterproductive to the future of cancer care to believe that the only acceptable approach to determining the absolute or relative clinical utility of a specific drug, regimen, device, or procedure, is through the conduct of a so-called evidence-based randomized trial.

Immunotherapy Not Ready for Prime Time in Ovarian Cancer

November 05, 2015

Early promising responses seen with immune checkpoint inhibitors for patients with ovarian cancer still need to be validated in larger randomized trials before a conclusion is made regarding their true efficacy.

Value-Based Care: Why Include Factors Beyond Oncologists' Control?

September 14, 2015

How can any analysis of the quality of cancer care being delivered by providers that focuses on a survival outcome as the ultimate measure of that quality-rather than on an evaluation of the optimization of the care process-be considered objectively valid and clinically meaningful?

New Ovarian Cancer Guidelines Include Surgery, Chemotherapy and Therapy Advancements

March 18, 2015

Recent advancements in the treatment of ovarian cancer, including surgical techniques, the approvals of bevacizumab and olaparib, and intraperitoneal chemotherapy, have led the National Comprehensive Cancer Network to make changes to their clinical practice guidelines.