Vol. 21/No. 17 | Oncology Live®

Expanded Lung Cancer Screening Criteria Would Boost Survival Outcomes

September 05, 2020

Under a draft recommendation proposed by the US Preventive Services Task Force, individuals who are at a high risk for developing lung cancer because of their smoking history would begin annual screening with low-dose computed tomography at aged 50 years.

New Era for Targeting HER2 Beckons in Breast Cancer and Beyond

September 03, 2020

Features

Precision medicine advancements are opening a new chapter in the development of anticancer therapies that target the HER2 pathway, resulting in 3 approvals for breast cancer in less than a year and raising hopes for attacking other cancer types.

Studies Explore a New Role for CDK4/6 Inhibition in HR+/HER2+ Breast Cancer and TNBC

September 02, 2020

Conference Highlights

Priyanka Sharma, MD, discusses how data from early clinical studies suggest a role for CDK4/6 inhibitor-based combinations in hormone receptor- positive, HER2-positive breast cancer and triple-negative breast cancer.

Liquid Biopsy Field Moves Forward But Faces Hurdles

September 02, 2020

Cover Story

Technological advancements are rapidly expanding the potential uses for blood-based liquid biopsies, but broad clinical adoption in cancer care hinges on improving the knowledge base of practicing oncologists and gathering prospective data to validate assays.

First Targeted Regimen Arrives for BRAF V600E-Mutant mCRC

September 01, 2020

Features

The approval of encorafenib in combination with cetuximab advances the metastatic colorectal cancer paradigm, introducing a biomarker-specific regimen for patients with pretreated BRAF V600E–mutant disease.

Prompt Diagnosis Is Vital in Treatment of Tenosynovial Giant Cell Tumors

September 01, 2020

During an OncLive Peer Exchange®, a panel of orthopedic experts provided a comprehensive overview of these tumors, including their epidemiology and differential diagnosis, optimal clinical workup, and the role of surgical management.

The Dilemma of New Evidence: When to Shift Gears

August 29, 2020

From the Editor

When is it appropriate to accept a specific strategy, either formally or informally, as a standard-of-care option in managing the treatment of patients with cancer in a particular clinical setting?