All Oncology News

The OncLive® News page includes the latest in clinical oncology news, including breaking regulatory decisions, clinical trial findings, pivotal and practice-changing data published in academic peer-reviewed journals, and more across solid and hematologic malignancies. Regulatory news includes new drug approvals by the FDA and European Union, priority review and breakthrough therapy designations, and orphan drug and fast track statuses.

Sentinel Lymph Node Test Has No Effect on Overall Survival in Women With Early-Stage Breast Cancer

July 28th 2011

It had been thought that removing the sentinel node and the surrounding lymph nodes would improve survival rates.

3 New Genetic Mutations Establish Hereditary Link in Esophageal Cancer

July 27th 2011

Three new genetic mutations have been identified in patients with Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC).

Flip Flops, Baseball Caps, and Skin Cancer

July 27th 2011

Sun exposure to usually-covered skin is yet another risk for skin cancer.

Erlotinib Extends PFS in EGFR-Positive Lung Cancer

July 25th 2011

Findings from a randomized phase III trial in China suggest erlotinib is suitable for first-line treatment in patients with EGFR mutation-positive NSCLC.

Ob-Gyn Physicians Support Mammograms Starting at Age 40

July 22nd 2011

The American College of Obstetricians and Gynecologists this week recommended annual mammography screenings for women starting at age 40.

Avastin Still Recommended by NCCN for Use Against Metastatic Breast Cancer

July 21st 2011

The NCCN voted to maintain the current recommendation and position on Avastin (bevacizumab) in its treatment of metastatic breast cancer.

FDA Advised Not to Approve Dapagliflozin for Diabetes

July 20th 2011

A panel voted 9-6 advising the FDA not to approve dapagliflozin, a diabetes drug that forces the body to dump sugar.

Trastuzumab and Chemotherapy Prolong Survival in Patients With Breast Cancer and CNS Metastases

July 18th 2011

Treatment with Herceptin, chemotherapy, or surgery extended the lives of patients with HER2-positive MBC following a diagnosis of CNS metastases.

Drug Shortages Are Not Unique to Oncology Practice

July 18th 2011

Shortages also are occurring in hospitals, and becoming increasingly frequent.

FDA Panel Unanimously Supports New Lymphoma Treatment

July 15th 2011

ODAC unanimously recommended accelerated approval for brentuximab vedotin (Adcetris) in 2 types of lymphoma.

Patients With Bladder Cancer Not Getting Recommended Care

July 14th 2011

Study results reveal that only a small fraction of patients with high-grade, noninvasive bladder cancer receive the appropriate treatment.

BOLERO-2 Halted After Positive Interim Analysis

July 13th 2011

A phase III study of Afinitor (everolimus) tablets combined with exemestane in women with breast cancer revealed that the regime significantly extended PFS.

Study Shows Estrogen Not the Only Hormone Feeding Tumors in Breast Cancer

July 13th 2011

Although researchers know that estrogen plays a role in most cases of breast cancer, they don't fully understand how.

FDA Approves First Fentanyl Nasal Spray for Breakthrough Cancer Pain

July 12th 2011

FDA approvad Lazanda (fentanyl) nasal spray for the management of breakthrough pain in adult cancer patients.

Afinitor Halves SEGA Tumor Size in Patients With Tuberous Sclerosis

July 11th 2011

In the phase III EXIST-1 trial, Afinitor reduced the size of SEGAs-benign brain tumors associated with TSC-by ≥50% in one-third of patients.

Amgen Seeks to Expand Xgeva's FDA Approval

July 11th 2011

A pivotal phase III study found that men with CRPC experienced prolonged bone metastasis–free survival with Xgeva versus placebo.

New Cigarette Warnings

July 11th 2011

Will graphic images and stronger warnings decrease cigarette smoking?

New Crizotinib Results Show Positive Outcomes

July 8th 2011

Crizotinib demonstrated marked antitumor activity among patients with advanced ALK-positive non–small cell lung cancer.

Colon Cancer Screening Saves Lives Yet Screening Rates Remain Below Standard

July 7th 2011

Almost 1 in 3 adults in the United States do not get screened regularly.

NCI Examines Cediranib to Fight Metastatic Prostate Cancer

July 7th 2011

Prostate cancer metastases, or cancer growing outside the prostate glands, can occur in any organ but is seen most frequently in the bone.

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