Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Enhanced Immune Response Seen With Radiation/Ipilimumab Combo in Melanoma

October 24th 2015, 5:00am

ASTRO Annual Meeting

Proinflammatory cytokines were elevated in patients with melanoma undergoing the combination treatment of radiation therapy and the systemic anti–CTLA-4 immunotherapy, ipilimumab.

Mayo Study Characterizes Pembrolizumab-Induced Thyroiditis

October 23rd 2015, 2:28pm

International Thyroid Congress

Abnormal thyroid function tests were reported in up to 15% of patients treated with the PD-1 inhibitor pembrolizumab.

Coexisting BRAF/TERT Mutations Predict Aggressive Thyroid Cancer

October 23rd 2015, 1:21pm

International Thyroid Congress

Coexisting mutations in BRAF and TERT may be associated with an aggressive phenotype and higher recurrence rates for patients with locally advanced well-differentiated thyroid cancers.

Nodule Size Should Not Determine Biopsy Decision in Thyroid Cancer

October 23rd 2015, 12:56pm

International Thyroid Congress

The recent American Thyroid Association guidelines to abstain from cytological evaluation by biopsy for patients with thyroid cancer on the basis of having thyroid nodules ≤1 cm is not advisable.

Dr. Johung on Prognosis of Patients With ALK-Rearranged NSCLC and Brain Metastases

October 23rd 2015, 8:22am

ASTRO Annual Meeting

Kimberly L. Johung, MD, PhD, assistant professor of Therapeutic Radiology, Gastrointestinal Cancer Program, Yale Cancer Center, discusses a study that examined the prognosis of patients with ALK-rearranged non–small cell lung cancer and brain metastases.

Pazopanib's Activity in Thyroid Cancer Not Predicted by Thyroglobulin

October 22nd 2015, 2:35pm

International Thyroid Congress

Pazopanib demonstrated significant clinical activity for patients with RAI-refractory differentiated thyroid cancer; however, a predictive biomarker for the therapy could not be uncovered.

Tumor Profiling Identifies Potential Biomarkers for Vandetanib in MTC

October 22nd 2015, 2:10pm

International Thyroid Congress

Researchers have identified molecular markers in medullary thyroid cancer that were associated with response to vandetanib and the development of metastases.

Dr. Stephen Huang on Challenges in Pediatric Thyroid Cancer

October 22nd 2015, 1:12pm

International Thyroid Congress

Stephen Huang, MD, Associate Professor of Pediatrics, Harvard Medical School, Dana Farber Cancer Institute, discusses the challenges of pediatric thyroid cancer.

Vemurafenib/Sorafenib Combo Shows Promise in Papillary Thyroid Carcinoma

October 22nd 2015, 12:38pm

International Thyroid Congress

Dual targeting of BRAF V600E–positive papillary thyroid carcinoma with the anti-BRAF V600E agent vemurafenib and the angiogenesis inhibitor sorafenib showed promising clinical activity.

Dr. Brose on Lenvatinib in Differentiated Thyroid Cancer

October 22nd 2015, 9:49am

International Thyroid Congress

Marcia Brose, MD, PhD, associate professor of Otorhinolaryngology, Head and Neck Surgery, at the Hospital of the University of Pennsylvania, discusses survival benefit and possible combination strategies with the lenvatinib in patients with radioactive iodine refractory differentiated thyroid cancer.

Radiation Underutilized in Low-Grade Follicular Lymphoma

October 22nd 2015, 6:05am

ASTRO Annual Meeting

The use of radiation therapy has declined despite evidence demonstrating it is often more beneficial than single-agent chemotherapy or observation-alone in patients with low-grade follicular lymphoma.

Dr. Valderrabano on Understanding Cancer Risk in Indeterminate Thyroid Nodules

October 21st 2015, 3:12pm

International Thyroid Congress

Pablo Valderrabano, MD, Clinical Research Fellow at Moffitt Cancer Center, discusses molecular markers in thyroid nodules and their connection to cancer incidence.

Dr. Aditi Kumar on Aggressive Multimodal Therapy in Anaplastic Thyroid Cancer

October 21st 2015, 2:02pm

International Thyroid Congress

Aditi Kumar, MD, endocrinology fellow at the University of Mississippi, discusses aggressive multimodal therapy in anaplastic thyroid cancer. A study conducted at the Mayo Clinic, where Kumar was previously a fellow, looked at 29 patients with stage IV, A, B and C anaplastic thyroid cancer, a rare form of thyroid cancer with poor outcomes. Often, patients are not treated at this stage, as options are limited and toxicities from treatments can be high, says Kumar.

Second-Line Cabozantinib Effective in RAI-Refractory DTC

October 21st 2015, 12:37pm

International Thyroid Congress

The oral multikinase inhibitor cabozantinib showed promise as a second- or third-line therapy in patients with advanced radioactive iodine-refractory differentiated thyroid cancer.

Lenvatinib PFS Benefit in DTC Maintained Across Metastasis Sites

October 21st 2015, 11:19am

International Thyroid Congress

The progression-free survival benefit with lenvatinib in radioactive iodine-refractory differentiated thyroid cancer was observed across common sites of metastasis.

Survey Reveals Potential Overuse of Thyroid Nodule Biopsy

October 21st 2015, 9:48am

International Thyroid Congress

A large survey of endocrinologists found wide variation in management strategies for thyroid nodules that were frequently misaligned with current guidelines, particularly for biopsies by fine-needle aspiration.

Dr. Umamaheswar Duvvuri on Impact of Multiple Genetic Mutations in Advanced Thyroid Cancer

October 20th 2015, 3:08pm

International Thyroid Congress

Umamaheswar Duvvuri, MD, PhD, Assistant Professor of Otolaryngology (ENT) at the University of Pittsburgh Medical Center, talks about potential genetic signatures for locally advanced, well differentiated thyroid cancers.

Dr. Manisha Shah on Cabozantinib Impact on Tumor Shrinkage in Differentiated Thyroid Cancer

October 20th 2015, 2:20pm

International Thyroid Congress

Manisha Shah, MD, Professor of Oncology at Ohio State University Medical Center, College of Medicine discusses cabozantinib in patients with radioiodine- refractory differentiated thyroid cancer.

Dr. Kunz on Potential of Immunotherapy in Neuroendocrine Tumors

October 17th 2015, 9:46am

NANETS Symposium

Pamela L. Kunz, MD, assistant professor of Medicine (Oncology), Stanford University School of Medicine, discusses the potential of immunotherapy in the treatment of patients with neuroendocrine tumors (NETs).

Everolimus Shows Robust Activity in Lung/GI NETs

October 17th 2015, 9:40am

NANETS Symposium

Everolimus improved progression-free survival by 7.1 months compared with placebo in patients with lung/gastrointestinal (GI) neuroendocrine tumors, representing a 52% reduction in the risk of progression or death.