ASTRO Annual Meeting | Conference

Dr. Iyengar on the Rationale Behind Hypofractionated Radiation in NSCLC

October 18th 2016

Puneeth Iyengar, MD, radiation oncologist, University of Texas Southwestern Medical Center, discusses the rationale behind the use of hypofractionated radiation as a treatment for patients with non–small cell lung cancer.

Dr. Daniel Eidelberg Spratt on Risk Factors in Prostate Cancer

October 17th 2016

Daniel Eidelberg Spratt, MD, assistant professor, radiation oncology, University of Michigan Health System, discusses challenges regarding the classification of risk groups in prostate cancer.

Concurrent Chemoradiation, Radical Cystectomy Demonstrate Similar Median OS Rates in Urothelial Cancer

October 14th 2016

In a propensity-matched analysis of a national cancer registry, patients who underwent radical cystectomy or concurrent chemoradiation to treat urothelial cancer demonstrated statistically similar median overall survival rates. Further analysis suggests that the hazard ratios between the two treatments change over time and is hypothesis generating.

Computer Simulation Helps Plan Transducer Placement in Glioblastoma

October 13th 2016

For patients who are likely to experience contiguous recurrence of glioblastoma, a new computer simulation using tumor treating fields and employing a personalized transducer array, delivered electric field intensities that exceeded therapeutic intensities in 3 different tumor locations. The findings may aid treatment planning when using the NovoTAL System, which optimizes therapeutic delivery in 2 orthogonal directions to the gross tumor volume and proximal peri-tumoral brain zone.

Minimal Toxicities Reported in Extreme Hypofractionated Comparison Trial in Prostate Cancer

October 10th 2016

Men with intermediate prostate cancer who received extreme hypofractionated radiotherapy reported a low incidence of side effects, with no significant differences compared with a similar cohort of men who received conventional fractionation after 2 years of treatment.

Radiation and TGFβ Inhibition Combo Elicits Activity in Metastatic Breast Cancer

October 7th 2016

A strategy to stimulate an immune response in radiation-damaged tumor cells resulted in preliminary evidence of activity—including longer survival—in a small clinical trial of patients with metastatic breast cancer.

No Benefit Observed From Combined Irradiation in Intermediate-Risk Prostate Cancer

October 7th 2016

The addition of external-beam radiotherapy to interstitial brachytherapy failed to reduce prostate cancer progression compared to brachytherapy alone in men with intermediate-risk disease.

H-RT Reduces Treatment Time by One-Third in Low-Risk Prostate Cancer

October 5th 2016

Study results that examined patient-reported outcomes and quality of life measures demonstrate that hypofractionated radiotherapy is a viable, safe, and value-added alternative to patients with low-risk prostate cancer.

KRAS-Variant HNSCC Outcomes May Improve With Cetuximab

October 4th 2016

Patients with head and neck cancer whose disease is associated with KRAS variant had significantly better progression-free survival and overall survival when treated with the monoclonal antibody cetuximab, according to findings of a retrospective analysis of a randomized trial.

Study Adds Clarity to Irradiation Role in Low-Risk Meningioma

October 1st 2016

Patients with low-risk meningioma had a 3-year progression-free survival that modestly exceeded expectations after gross total resection followed by observation.

Fewer GI, GU Toxicities With Postoperative Pelvic IMRT in Gynecologic Malignancies

September 29th 2016

Patients with endometrial and cervical cancer reported significantly less acute gastrointestinal toxicity when treated with pelvic intensity-modulated radiation therapy as opposed to standard pelvic radiation therapy.

RT Plus Chemo Significantly Improves PFS in Follicular Lymphoma

September 28th 2016

Chemoradiation for early-stage, low-grade follicular lymphoma led to significant improvement in progression-free survival compared with involved-field radiotherapy alone.

Dr. Marshall on ASCENDE-RT Trial for Prostate Cancer

January 13th 2016

David T. Marshall, MD, MS, professor, director, Medical Residency Program, Department of Radiation Oncology, Medical University of South Carolina, discusses the ASCENDE-RT trial, which compared dose-escalated external beam radiation therapy versus low-dose-rate brachytherapy for men with unfavorable-risk localized prostate cancer.

Dr. Murphy on Glioma Prognostic Factors in Younger Patients

January 6th 2016

Erin Murphy, MD, associate staff, Department of Radiation Oncology, Cleveland Clinic, discusses a study examining prognostic factors of patients with glioma.

Dr. Goodman on Ongoing Clinical Trials in Radiation Oncology

January 5th 2016

Karyn A. Goodman, MD, radiation oncologist, professor in the Department of Radiation Oncology, University of Colorado Denver, discusses ongoing trials in the field of radiation oncology.

Dr. Ciezki on Common Advanced Disease Sites in Patients

December 24th 2015

Jay Ciezki, MD, Department of Radiation Oncology, Cleveland Clinic, discusses an analysis of patients with various malignancies who commonly presented with advanced disease.

Dr. Kuske on APBI Via Multicatheter Interstitial Brachytherapy

November 26th 2015

Robert R. Kuske, MD, radiation oncologist, Arizona Breast Cancer Specialists, discusses the analysis of the Pooled Registry of Multicatheter Interstitial Sites Experience, which examined the safety of accelerated partial breast irradiation via multicatheter interstitial brachytherapy.

Dr. Vicini on Accelerated Partial Breast Irradiation in Low-Risk Breast Cancer

October 29th 2015

Frank A. Vicini, MD, radiation oncologist, 21st Century Oncology of Michigan, discusses a European study that examined the efficacy of accelerated partial breast irradiation versus conventional whole breast irradiation in patients with low-risk breast cancer.

Dexamethasone Lessens Bone Pain Flare in Metastatic Disease

October 25th 2015

The oral corticosteroid dexamethasone significantly decreased flares of bone pain when added to radiation therapy in patients with metastatic cancer.

Accelerated Partial Breast Irradiation Demonstrates Efficacy in Low-Risk Breast Cancer

October 25th 2015

Rates of overall survival, disease-free survival, and local control were found to be comparable in select patients with early-stage breast cancer who underwent accelerated partial breast irradiation using multicatheter brachytherapy versus conventional whole breast irradiation.