Prostate Cancer | Specialty

The OncLive Prostate Cancer condition center page is a comprehensive resource for clinical news and expert insights on how to approach treatment for patients with nonmetastatic, castration-resistant, or castration-sensitive prostate cancer. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, ongoing research, and treatment advances with androgen receptor inhibitors, PARP inhibitors, and more in prostate cancer.

Combining Radiotherapy With Anti-Androgen Improves Prostate Cancer Survival

October 24th 2015

The additon of hormonal therapy to salvage radiotherapy demonstrated a significant survival benefit in patients with prostate cancer recurrence after radical prostatectomy, according to long-term follow-up data from a randomized trial.

Breakthrough Designation in ALL, HIFU FDA Approval, Breast Cancer Screening Update, and More

October 23rd 2015

Prostate Cancer: Every Action Has a Reaction

October 14th 2015

For those who think that men can’t die of prostate cancer, they can spend the day with me in clinic and meet some of the bravest men on the planet who are in the fight of their lives and are unfortunately afflicted with advanced metastatic prostate cancer.

High-Intensity Ultrasound Device for Prostate Surgery Clears FDA Hurdle

October 13th 2015

The FDA has issued a de novo clearance for a minimally invasive high-intensity focused ultrasound for prostate tissue ablation called Sonablate 450 and marketed by SonaCare Medical, LLC.

Dr. Maha Hussain on Novel Approaches in Prostate Cancer

October 8th 2015

Dr. Poortmans on Impact of Multidisciplinary Approach on Side Effect Management

October 7th 2015

Philip Poortmans, MD, PhD, head of Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands, and president of European Society for Therapeutic Radiology and Oncology, discusses the impact of a multidisciplinary approach on survivorship and side effect management for patients with prostate cancer.

Zoledronic Acid Does Not Add to Upfront Docetaxel Survival Benefit in Advanced Prostate Cancer

October 5th 2015

An updated analysis of the STAMPEDE trial upholds the survival benefit observed with early use of docetaxel in advanced prostate cancer, but does not support the introduction of zoledronic acid.

Changes in Prostate Cancer Presentation for Radiation Oncology Care

October 3rd 2015

USPSTF guidelines may have decreased the number of patients presenting with prostate cancer for radiation oncology care, particularly those with low-risk disease, without a short-term increase in higher-risk disease.

Dr. Ferrari on LBH589 and Bicalutamide in CRPC

October 2nd 2015

Anna C. Ferrari, MD, professor, co-director, GU Research Program, Departments of Medicine (Cancer Center) and Medicine (Residency Program), discusses a study that examined the efficacy of LBH589 and bicalutamide in patients with castration-resistant prostate cancer.

Tasquinimod Discontinuation in mCRPC Discussed at 2015 ECC

September 30th 2015

Tasquinimod, a drug that showed great promise in phase II trials, failed to improve overall survival in a phase III trial in men with treatment-naïve metastatic castration-resistant prostate cancer.

One Clinic's Multidisciplinary Approach Optimizes the Use of Radium-223

September 20th 2015

With the advancement of radium-223 comes questions and controversy regarding optimal treatment sequencing, combination therapy, and appropriate patient selection.

Dr. Sartor on Significance of Radium-223 for Community Oncologists

September 16th 2015

Oliver Sartor, MD, medical oncologist, Tulane University School of Medicine, discusses key points for community oncologists regarding radium-223 for the treatment of prostate cancer.

Radium-223 Poised to Move Beyond Prostate Cancer

August 27th 2015

The alpha particle–emitting radiopharmaceutical radium-223 (Xofigo) is set to expand beyond prostate cancer, given the agent's potent efficacy and mild toxicity profile for patients with osteoblastic metastases.

Medivation Acquires BioMarin's PARP Inhibitor Talazoparib

August 25th 2015

Medivation has announced that it will purchase the PARP inhibitor talazoparib (BMN-673) from BioMarin Pharmaceutical for $410 million, with additional milestone and royalty payments of up to $160 million.

Dr. Renzulli on Expanded Access Program With Radium-223

August 24th 2015

Joseph F. Renzulli, II, MD, FACS, assistant professor of surgery (urology) clinical, Alpert Medical School, discusses the expanded access program in the United States for radium-223 dichloride in patients with metastatic castration-resistant prostate cancer.

Start Discussions About Palliative Care Upon Initial Metastatic Diagnosis

August 11th 2015

In the urologic oncology field, urologists can play an important role in successful comprehensive care by incorporating palliative care in their treatment regimens.

Early Docetaxel, ADT Combo Increases Survival in Advanced Prostate Cancer

August 10th 2015

Concomitant therapy with docetaxel and androgen deprivation therapy initiated at the start of treatment for men with metastatic prostate cancer resulted in an increased survival of 13.6 months compared with men who received ADT alone.

Dr. Shore on Lack of Reported Symptoms in Men With Prostate Cancer

August 10th 2015

Neal D. Shore, MD, medical director, Carolina Urologic Research Center, managing partner, Atlantic Urology Clinics, discusses preliminary results of the Harris poll, which surveyed how men with advanced prostate cancer communicate with their practitioners.

New Diagnoses of Prostate Cancer Decline Nearly 30% Following USPSTF PSA Decision

August 6th 2015

New diagnoses of prostate cancer cases declined nearly 30% after the United States Preventive Services Task Force recommended against routine prostate-specific antigen screening for men.

Study Says Urologists in Solo Practice May Overuse Gonadotropin Agonists

August 5th 2015

Urologists who are in solo practice or not affiliated with a medical school may overuse primary gonadotropin-releasing hormone for men with localized prostate cancer.