Prostate Cancer | Specialty

The OncLive Prostate Cancer condition center page is a comprehensive resource for clinical news and expert insights on how to approach treatment for patients with nonmetastatic, castration-resistant, or castration-sensitive prostate cancer. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, ongoing research, and treatment advances with androgen receptor inhibitors, PARP inhibitors, and more in prostate cancer.

Androgen Receptor Signaling and Its Role in Driving Prostate Cancer Metastasis

February 26th 2024

Expert perspectives on androgen receptor signaling and its role in fueling prostate cancer metastasis along with a whiteboarding animation depicting this process.

Swissmedic Accepts Marketing Authorization Application for Piflufolastat (18F) for Prostate Cancer

February 22nd 2024

Swissmedic has accepted for review a marketing authorization application seeking the approval of Piflufolastat (18F) for prostate cancer.

Dr Gong on the EMBARK Trial Investigating Enzalutamide in nmCSPC

February 20th 2024

Jun Gong, MD, discusses the significance of the phase 3 EMBARK study of enzalutamide in nonmetastatic castration-sensitive prostate cancer.

Treatment Selection in Metastatic and Castration Resistant Prostate Cancer Optimizing Outcomes and Preserving Patient Quality of Life

February 19th 2024

Drs. Shore & McKay discuss treatment selection for metastatic & castration-resistant prostate cancer, the current landscape, and key factors guiding personalized treatment decisions.

Predicting Risk and Guiding Care: Biomarkers & Genetic Testing in Prostate Cancer

February 19th 2024

GU medical oncologist Dr. Rana McKay and urologist Dr. Neal Shore explore how predictive biomarkers and genetic testing are informing risk assessment and guiding personalized treatment decisions in clinical practice

Dr Shore on the Implications of the FDA Approval of Enzalutamide for nmCSPC

February 16th 2024

Neal Shore, MD, FACS, discusses the implications of the FDA approval of enzalutamide for patients with nonmetastatic castration-sensitive prostate cancer.

Dr Shore on the Background and Outcomes of the EMBARK Trial in nmCSPC

February 15th 2024

Neal Shore, MD, FACS, discusses the phase 3 EMBARK study of enzalutamide in patients with nonmetastatic castration-sensitive prostate cancer.

APEX-01 Looks to Add First PSMA-Directed ADC to Treatment Paradigm in mCRPC

February 13th 2024

John Shen, MD, discusses the phase 1/2 APEX-01 trial of ARX517 in metastatic castration-resistant prostate cancer.

FDA Grants Fast Track Designation to BXCL701 for Small Cell Neuroendocrine Prostate Cancer

February 12th 2024

BXCL701 has been granted fast track designation for select patients with metastatic small cell neuroendocrine prostate cancer by the FDA.

rPFS and cPFS May Act as Surrogate OS End Points in Phase 3 mHSPC Clinical Trials

February 9th 2024

Radiographic and clinical progression-free survival may be surrogates for overall survival in hormone-sensitive prostate cancer clinical trials.

Apalutamide Plus ADT Improves PSA-PFS in High-Risk Biochemically Relapsed Prostate Cancer

February 9th 2024

Apalutamide plus androgen deprivation therapy improved prostate-specific antigen progression-free survival in castration-sensitive prostate cancer.

Optimizing Care of Patients With Advanced Prostate Cancer: Conclusion

February 9th 2024

Summarizes the main points and benefits of multidisciplinary prostate cancer care.

Dr Takvorian on the Evolution of PARP Inhibitors in Prostate Cancer

February 8th 2024

Samuel U. Takvorian, MD, MS, discusses the evolution of regulatory decisions regarding the use of PARP inhibitors for patients with prostate cancer.

HPN328 Shows Clinical Activity and Tolerability in Neuroendocrine Prostate Cancer

February 8th 2024

HPN328, was well tolerated and elicited responses in patients with neuroendocrine prostate cancer and other neuroendocrine neoplasms.

Dr Gong on the Current Treatment Armamentarium in mHSPC

February 7th 2024

Jun Gong, MD, discusses the current treatment armamentarium for patients with metastatic hormone-sensitive prostate cancer.

Tinengotinib Shows Early Tolerability, Efficacy Signals in Heavily Pretreated mCRPC

February 5th 2024

Tinengotinib elicited responses with a manageable safety profile in heavily pretreated patients with metastatic castration-resistant prostate cancer.

Clinical Case 4: Radiation Therapy

February 2nd 2024

Covers key factors in deciding on radiation treatment.

Clinical Case 3: Extensive Lymph Node Disease

February 2nd 2024

Discusses treatment options for advanced metastatic disease.

Dr Sharma on Questions Regarding the Optimal Use of Triplet Therapies in HSPC

February 2nd 2024

Janaki Neela Sharma, MD, discusses data with triplet therapies in patients with hormone-sensitive prostate cancer.

Clinical Case 2: Solitary Lymph Node

January 30th 2024

Looks at approaches for isolated lymph node involvement.