Ovarian Cancer | Specialty

The OncLive Ovarian Cancer condition center page is a comprehensive resource for clinical news and expert insights on ovarian cancer and evolving treatment approaches, including PARP inhibitors, antibody-drug conjugates, chemotherapy and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in ovarian cancer.

Is the Median All We Should Offer Our Patients?

February 28th 2018

Although median survival is a reasonable endpoint to highlight, it is only 1 of many relevant outcome factors to discuss, and, most important, this mathematical figure simply does not define the survival of any particular patient.

EU Panel Recommends Olaparib Tablets for Ovarian Cancer, Regardless of BRCA Status

February 24th 2018

The European Medicines Agency’s Committee for Medicinal Products for Human Use has recommended approval of olaparib tablets (Lynparza) as a maintenance therapy for patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer.

Dr. Moore Discusses Combinations in Ovarian Cancer

February 23rd 2018

Kathleen N. Moore, MD, assistant professor, The Stephenson Cancer Center, The University of Oklahoma, discusses combinations in the treatment of patients with ovarian cancer.

Dr. Crane on Combinations With PARP Inhibitors in Ovarian Cancer

February 17th 2018

Erin K. Crane, MD, MPH, gynecologic oncologist, Levine Cancer Institute, Carolinas HealthCare System, discusses combinations with PARP inhibitors in ovarian cancer.

Dr. O'Malley Discusses the Current Role of PARP Inhibitors in Ovarian Cancer

February 14th 2018

David O'Malley, MD, a professor in the Department of Obstetrics and Gynecology at The Ohio State University Comprehensive Cancer Center, discusses the current role for PARP inhibitors for patients with ovarian cancer.

Immunotherapy Combos on Horizon for Ovarian Cancer

February 11th 2018

Several phase III studies are exploring immunotherapy combinations with the potential to disrupt the systemic treatment paradigm for patients with ovarian cancer.

PARP Combinations Offer New Opportunities in Ovarian Cancer

February 11th 2018

PARP inhibitor combination regimens have the potential to enhance the relatively modest benefit offered by several monotherapy approaches used for the treatment of patients with ovarian cancer.

Dr. Arend on the Rationale of Novel Combinations in Gynecologic Cancer

February 10th 2018

Rebecca C. Arend, MD, assistant professor, UAB School of Medicine, UAB Department of Obstetrics and Gynecology, UAB Comprehensive Cancer Center, discusses the rationale behind novel combination strategies for patients with gynecologic cancer.

PARP Combos With Bevacizumab, Immunotherapy in Development for Ovarian Cancer Treatment

February 10th 2018

Rebecca C. Arend, MD, discussed novel combinations being investigated for the treatment of patients with ovarian cancer.

Expert Highlights PARP Inhibitor Advancements in Ovarian Cancer, Points to Future Combos

February 10th 2018

David O'Malley, MD, discusses the excitement surrounding PARP inhibitors for patients with ovarian cancer.

Dr. Moore on Immunotherapy and PARP Combinations in BRCA-Mutated Ovarian Cancer

February 10th 2018

Kathleen N. Moore, MD, assistant professor, The Stephenson Cancer Center, The University of Oklahoma, discusses combinations of immunotherapy with PARP inhibitors for patients with BRCA-mutated ovarian cancer.

Immunotherapy Combinations Slated to Pave the Way in Ovarian Cancer Treatment

February 9th 2018

Kathleen Moore, MD, discusses combination strategies with immunotherapy for patients with ovarian cancer.

Dr. Al-Niaimi on the Future Role of Cytoreductive Surgery in Ovarian Cancer

February 9th 2018

Ahmed N. Al-Niaimi, MD, assistant professor of obstetrics and gynecology, University of Wisconsin School of Medicine and Public Health, discusses the future role for cytoreductive surgery for the treatment of patients with ovarian cancer.

Dr. Crane on the Impact of PARP Inhibitors in Ovarian Cancer

February 9th 2018

Erin K. Crane, MD, MPH, gynecologic oncologist, Levine Cancer Institute, Carolinas HealthCare System, discusses the impact of PARP inhibitors for patients with ovarian cancer.

Dr. Markman on Overall Survival as an Endpoint in Ovarian Cancer Trials

February 7th 2018

Maurie Markman, MD, president of Medicine and Science, Cancer Treatment Centers of America, editor-in-chief, OncologyLive, discusses overall survival as an endpoint in ovarian cancer clinical trials.

Prexasertib Promising in BRCA Wild-Type Ovarian Cancer

February 2nd 2018

Prexasertib (LY2606368) induced a 29% response rate with acceptable tolerability in women with measurable, recurrent high-grade serous or high-grade endometrioid ovarian carcinoma.

Inheritance Matters: The Race to Prevent New Ovarian Cancer Cases

January 31st 2018

Emerging data have confirmed that ovarian cancer is a much more heterogeneous disease than previously recognized.

Biomarkers Go Beyond "All or None" Equation

January 31st 2018

The FDA’s recent approvals of novel anti-PARP agents as maintenance therapy for patients with previously treated advanced ovarian cancer highlight an issue that has received inadequate attention in the peer-reviewed oncology literature.

PARP Inhibition Enhanced Through Combination in Ovarian Cancer

January 27th 2018

Mansoor Raza Mirza, MD, discusses the initial findings and next steps for the promising niraparib plus bevacizumab combination in ovarian cancer, as well as overall advances with PARP inhibitors in the field.

HIPEC Improves Survival in Advanced Ovarian Cancer

January 25th 2018

Adding hyperthermic intraperitoneal chemotherapy to interval cytoreductive surgery improved relapse-free survival and overall survival for women with newly diagnosed stage III epithelial ovarian cancer.