Non-Hodgkin Lymphoma | Specialty

Axi-Cel Elicits 92% ORR in Indolent Non-Hodgkin Lymphoma

December 5th 2020

December 5, 2020 - Axicabtagene ciloleucel demonstrated high rates of durable responses in patients with indolent non-Hodgkin lymphoma.

Selinexor Shows Clinical Benefit Across Age Groups in Relapsed/Refractory DLBCL

December 5th 2020

December 5, 2020 - Selinexor demonstrated a clinical benefit in patients with relapsed/refractory diffuse large B-cell lymphoma, regardless of age.

Treatment Considerations in Newly Diagnosed CLL

December 4th 2020

Drs Stilgenbauer and Ghia provide insight on initial treatment considerations for patients with newly diagnosed chronic lymphocytic leukemia.

Dr. Shah on Dosing Tandem Receptor CAR T-Cell Therapy in B-Cell Malignancies

December 3rd 2020

Nirav N. Shah, MD, associate professor​, Medical College of Wisconsin, discusses ​the dosing of tandem receptor CAR T-cell therapy in B-cell malignancies.

Panelists Parse Out Answers to Key Questions in Hematologic Malignancies

November 25th 2020

Stephen A. Strickland, MD, BS, MS, MSCI, relays insightful questions from the audience to the speakers, who provided insight into how they are navigating the evolving treatment landscape of hematologic malignancies.

FDA Grants Priority Review to Loncastuximab Tesirine for Relapsed/Refractory DLBCL

November 20th 2020

November 20, 2020 - The FDA has granted a priority review designation to a biologics license application for loncastuximab tesirine for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma.

COVID-19 Delays FDA Review of Liso-Cel for Relapsed/Refractory Large B-Cell Lymphoma

November 17th 2020

November 17, 2020 - The review of the biologics license application for the CAR T-cell product lisocabtagene maraleucel for the treatment of adult patients with relapsed/refractory large B-cell lymphoma following at least 2 previous therapies has been delayed.

Reddy Reviews Paradigm Shifts in CD30-Positive PTCL, Next Steps for Research

November 16th 2020

Nishitha M. Reddy, MD, MBBS, discusses the significance of the ECHELON-2 trial in peripheral T-cell lymphoma, the need for novel therapies for those with CD30-negative disease, and the excitement surrounding duvelisib in the relapsed/refractory setting.

The Future of CAR T-Cell Therapy in Diffuse Large B-Cell Lymphoma

November 6th 2020

Impact of COVID-19 on CAR T-Cell Therapy for R/R DLBCL

November 6th 2020

Real-World Data for CAR T-Cell Therapy for R/R DLBCL

November 6th 2020

CAR T-Cell Therapy Clinical Trials for R/R DLBCL

November 6th 2020

Mechanism of CAR T Cells in R/R Diffuse Large B-Cell Lymphoma

November 6th 2020

Overview of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

November 6th 2020

Choosing the Optimal Frontline Approach for Low-Grade Follicular Lymphoma

November 4th 2020

Frontline treatment decisions for patients with follicular lymphoma can be guided by a general framework; the choice of therapy is often based on several factors such as indications of therapy, bulk of disease, comorbidities, and toxicity.

Making Progress Against Relapsed/ Refractory DLBCL Without CAR T

November 3rd 2020

A panel of lymphoma experts discuss several novel agents for relapsed/ refractory diffuse large B-cell lymphoma, some of which have been recently approved.

Off-the-Shelf CAR T-Cell Product CTX110 Shows Early Activity in Relapsed/Refractory CD19+ B-Cell Malignancies

October 23rd 2020

The investigational wholly-owned allogeneic CAR T-cell therapy CTX110 demonstrated dose-dependent efficacy and responses in patients with relapsed/refractory CD19-positive B-cell malignancies.

Copanlisib/Rituximab Prolongs PFS in Relapsed Indolent Non-Hodgkin Lymphoma

October 15th 2020

Copanlisib in combination with rituximab prolonged progression-free survival in patients with non-Hodgkin lymphoma who relapsed following 1 or more previous lines of rituximab-based therapy.

Mogamulizumab Significantly Boosts Outcomes in CTCL With Blood Involvement

October 13th 2020

Higher levels of blood tumor involvement were linked with more favorable outcomes in patients who received treatment with mogamulizumab compared with vorinostat in patients with 2 types of cutaneous T-cell lymphoma.

Dr. Martin on the Need for Head-to-Head Comparisons of BTK Inhibitors in MCL

October 12th 2020

Peter Martin, MD, discusses the need for head-to-head comparison of BTK inhibitors in mantle cell lymphoma.