Myeloproliferative Neoplasms | Specialty

The OncLive Myeloproliferative Neoplasms condition center is a comprehensive resource for clinical news and expert insights on myeloproliferative neoplasms, including myelofibrosis, polycythemia vera, and essential thrombocythemia. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in myeloproliferative neoplasms.

Dr. Saint Fleur-Lominy on Emerging Agents in MPNs

March 19th 2020

Shella Saint Fleur-Lominy, MD, PhD, an assistant professor in the Department of Medicine at NYU Langone Health

Ruxolitinib Combo Shows Potential in Post-MPN AML, But Unmet Need Remains

March 18th 2020

Prithviraj Bose, MD, discusses the high unmet need in post-myeloproliferative neoplasms acute myeloid leukemia and the impact of findings from the phase I/II trial on current and future treatment strategies in the space.

Case Series Shows Feasibility of Haploidentical Transplant in High-Risk Myelofibrosis

March 17th 2020

Haploidentical allogeneic stem cell transplant is a viable treatment option for patients with myelofibrosis who have a higher risk for posttransplant complications and mortality.

Dr. Mesa on the Utility of Fedratinib for Patients With Myelofibrosis Who Progress on Ruxolitinib

March 16th 2020

Ruben Mesa, MD, discusses the utility of fedratinib for patients with myelofibrosis who progress on first-line ruxolitinib.

Dr. Nagalla on the Challenges of Managing Thrombocytopenia in MPNs

March 16th 2020

Srikanth Nagalla, MD, discusses the challenges of managing thrombocytopenia in patients with myeloproliferative neoplasms.

Dr. Saint Fleur-Lominy on Differences Between Ruxolitinib and Fedratinib in MPNs

March 16th 2020

Shella Saint Fleur-Lominy, MD, PhD, discusses the differences between ruxolitinib and fedratinib in the treatment of patients with myeloproliferative neoplasms.

Multidisciplinary Approach Required for Pulmonary Hypertension in Myelofibrosis

March 16th 2020

Juan C. Lopez-Mattei, MD, FACC, FASE, FSCCT, FSCMR, discusses the findings of the retrospective analysis of pulmonary hypertension in patients with myelofibrosis and their impact on clinical practice.

Dr. Mesa on Challenges With JAK Inhibitors in Myelofibrosis

March 14th 2020

Ruben Mesa, MD, discusses the challenges with using JAK inhibitors in myelofibrosis.

Dr. Garcia on the Managing Thrombocytopenia With Navitoclax in Myelofibrosis

March 10th 2020

Jacqueline S. Garcia, MD, instructor in medicine, Department of Medical Oncology, Harvard Medical School, and physician, Dana-Farber Cancer Institute, discusses the management of thrombocytopenia with navitoclax in patients with myelofibrosis.

Dr. Saint Fleur-Lominy on Impact of Ruxolitinib on Symptom Burden in MPNs

March 5th 2020

Shella Saint Fleur-Lominy, MD, PhD, discusses the effects ruxolitinib has on symptom burden in patients with myeloproliferative neoplasms.

MPN Research Efforts Expand Beyond JAK1/2 Inhibition, Transplant

March 4th 2020

Shella Saint Fleur-Lominy, MD, PhD, discusses some of the current and investigational treatment options for patients with myeloproliferative neoplasms.

Dr. Gerds on the State of Treatment in MPNs

March 3rd 2020

Aaron Gerds, MD, assistant professor of medicine in the Hematology and Medical Oncology Department at the Cleveland Clinic Taussig Cancer Institute, discusses the state of treatment in myeloproliferative neoplasms (MPNs).

Dr. Schroeder on Treatment Options for GVHD

February 28th 2020

Mark A. Schroeder, MD, discusses therapies currently available and being investigated to treat patients with graft-versus-host disease.

Dr. Rossetti on Symptom Management for MPNs

February 27th 2020

James M. Rossetti, DO, discusses symptom management for patients with myeloproliferative neoplasms.

Dr. Pemmaraju on Methods to Treat Anemia in MPNs

February 27th 2020

Naveen Pemmaraju, MD, discusses methods to address anemia in patients with myelodysplastic syndromes.

Dr. Kremyanskaya on Unmet Needs in Myelofibrosis

February 27th 2020

Marina Kremyanskaya, MD, PhD, discusses unmet needs in myelofibrosis.

Dr. Snyder on Transplant Updates in Myelofibrosis

February 26th 2020

David S. Snyder, MD, discusses updates in treating patients with myelofibrosis who undergo transplant.

Dr. Kuykendall on the Approval of Fedratinib in Myelofibrosis

February 26th 2020

Andrew T. Kuykendall, MD, discusses the additionof fedratinib to the treatment paradigm in myelofibrosis.

Dr. Garcia on the Tolerability of Navitoclax/Ruxolitinib in Myelofibrosis

February 26th 2020

Jacqueline S. Garcia, MD, discusses the tolerability of the combination of navitoclax plus ruxolitinib in patients with myelofibrosis.

Dr. Gerds on Luspatercept to Treat Anemia in Myelofibrosis

February 25th 2020

Aaron Gerds, MD, discusses results of a phase II trial examining the safety and efficacy of luspatercept as a treatment for anemia in patients with myelofibrosis.