Lung Cancer | Specialty

The OncLive Lung Cancer condition center page is a comprehensive resource for clinical news and expert insights on non–small cell lung cancer, small cell lung cancer, mesothelioma, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in lung cancer.

Treatment for Early-Stage NSCLC: Resection and Adjuvant Radiation Therapy

July 12th 2022

Shifting focus to early-stage NSCLC, expert panelists define the role of resection and consider when it is appropriate to utilize adjuvant radiation therapy.

Management of Adverse Events Associated with Durvalumab + Chemotherapy

July 11th 2022

Vivek Subbiah, MD, analyzes adverse events observed with durvalumab plus chemotherapy in patients with SCLC and how they can be managed.

Frontline Therapy for SCLC: The CASPIAN Trial of Durvalumab + Chemotherapy

July 11th 2022

Jared Weiss, MD, reviews data from the CASPIAN trial of durvalumab plus chemotherapy in patients with extensive-stage small cell lung cancer.

Prophylactic Approaches to the Management of CIM in ES-SCLC

July 8th 2022

Expert panelists review considerations in the prophylactic treatment of chemotherapy-induced myelosuppression with special attention paid to unmet needs related to the use of G-CSF and ESAs.

An Overview of Chemotherapy-Induced Myelosuppression in ES-SCLC

July 8th 2022

Two leaders in the management of ES-SCLC provide an overview of chemotherapy-induced myelosuppression including key risk factors and its effect on patient outcomes.

Future Implications of ctDNA in the Management of NSCLC

July 7th 2022

A thoracic oncology expert provides perspective on ctDNA as a tool and its future as part of the NSCLC landscape.

Review of Recent Data on ctDNA From ASCO 2022

July 7th 2022

A comprehensive review of data presented at ASCO 2022 on ctDNA and MRD detection in NSCLC.

Two Key Uses for ctDNA in the Clinical Setting

July 7th 2022

Dr. Mark Kris shares insight on ctDNA and its use in detecting MRD in NSCLC.

Strategies for Monitoring Patients with NSCLC

July 7th 2022

Practical advice on monitoring options for patients with NSCLC treated with definitive radiation therapy or surgery.

Current Treatment Options for Patients with NSCLC

July 7th 2022

Mark G. Kris, MD, FASCO shares an overview of existing treatment options for patients with stage I-III non-small cell lung cancer.

Patient Profile 1: A 68-Year-Old Male with SCLC and Brain Metastases

July 6th 2022

Charu Aggarwal, MD, MPH, presents the profile of a patient with small cell lung cancer with brain metastases to spark a discussion on treatment approaches in the frontline setting.

Progress in the Treatment and Management of SCLC

July 6th 2022

The panel discusses how the field of small cell lung cancer treatment has changed in recent years.

A Growing Arsenal of NSCLC Treatments Take Aim at Oncogenic Fusions

July 5th 2022

A panel of experts discuss their perspectives on testing and targeted therapy for actionable mutations in non–small cell lung cancer.

Molecular Testing in Advanced-Stage NSCLC: Use of Liquid Biopsy

July 5th 2022

Expert oncologists briefly highlight the role of liquid biopsy in the setting of advanced-stage non–small cell lung cancer.

Use of Molecular Profiling in Early-Stage Non–Small Cell Lung Cancer

July 5th 2022

A focused discussion on the use of molecular profiling in early-stage non–small cell lung cancer to inform decisions on adjuvant and neoadjuvant strategies.

Duma Discusses the Unique Challenges of Women With Lung Cancer (Continued)

July 4th 2022

Dr Duma discusses improving diversity in trials and in oncology providers, how the oncology field fails women in general and women of color in particular, and the stress lung cancer puts on a woman’s home life.

ALRN-6924 Halts Development in P53-Mutant NSCLC, Advances in P53-Mutant Breast Cancer

July 1st 2022

Drug manufacturer Aileron plans to stop further enrollment into a phase 1b trial (NCT04022876) after the chemoprotective agent ALRN-6924 missed its composite primary end point for patients with advanced p53-mutant non–small cell lung cancer.

Biomarker in Liquid Biopsy for Lung Cancer Appears More Accurate in Predicting Immunotherapy Response Than Tumor Biopsy

July 1st 2022

Study findings could be developed into less-invasive method.

Duma Discusses the Unique Challenges of Women With Lung Cancer

June 30th 2022

Dr Duma discusses the leading causes of lung cancer in women, the ongoing failure to screen a sufficient number of women for lung cancer, and how gender bias interferes with treatment.

Durvalumab Plus Chemotherapy Improves pCR in Resectable NSCLC

June 30th 2022

Neoadjuvant treatment with durvalumab plus platinum-based chemotherapy led to a statistically significant improvement in pathologic complete response and major pathologic response compared with chemotherapy alone in patients with resectable non–small cell lung cancer, according to findings from a planned interim analysis of the phase 3 AEGEAN trial.