Immunotherapy in Melanoma | Specialty

Combination BRAF-MEK Inhibition With Dabrafenib and Trametinib for BRAF-Mutant Melanoma

September 10th 2014

It is estimated that in 2014 more than 76,000 people will be diagnosed with melanoma and approximately 9700 people will die from the malignancy.

Dr. Andtbacka on T-VEC Plus Ipilimumab in Unresected Melanoma

September 8th 2014

Robert H. I. Andtbacka, MD, CM, from Intermountain Healthcare and Huntsman Cancer Institute, discusses the safety and efficacy of T-VEC in combination with ipilimumab in patients with previously untreated, unresected stage IIIB-IV melanoma.

Novel Peptide Vaccine Safe, Effective in High-Risk Breast Cancer

September 6th 2014

A novel HER2-derived peptide vaccine designed to stimulate CD8+ cytotoxic T-lymphocytes reduced the rate of breast cancer recurrence and proved safe and well tolerated in the adjuvant setting.

Bristol-Myers Squibb Challenges Patent on Merck's Pembrolizumab

September 5th 2014

BMS has filed a lawsuit over Merck's newly approved immunotherapy drug pembrolizumab, contending that the much-heralded PD-1 inhibitor will infringe upon patents that Bristol-Myers holds on the groundbreaking technology.

FDA Approves Pembrolizumab for Advanced Melanoma

September 4th 2014

The FDA has approved pembrolizumab (Keytruda) as a treatment for patients with advanced or unresectable melanoma who are no longer responding to other drugs, making it the first PD-1 inhibitor to gain approval in the United States.

Patient-Derived Xenograft (PDX) Models as Avatars for Patient Response to Therapy

September 3rd 2014

The promise of personalized medicine in cancer will only be met once physicians have both the arsenal of therapeutics they need and a more complete understanding of genomic tumor profiles.

Update on Vismodegib's Place in the Treatment of Advanced BCC

August 18th 2014

Basal cell carcinoma (BCC) is the most common human malignancy and by far the most prevalent form of skin cancer, accounting for more than 80% of all cases.

Dr. Daniels Discusses the Findings of the 2007-2012 PROCLAIM National Registry

August 7th 2014

Gregory A. Daniels, MD, PhD, Associate Clinical Professor of Medicine, Division of Hematology-Oncology, University of California, San Diego, discusses the findings of the 2007-2012 PROCLAIM national registry

Immunotherapy Advances in Melanoma

July 28th 2014

Melanoma care has fortunately undergone a whirlwind of changes over the past several years. Novel immunotherapies are perhaps the most exciting recent development in cancer care because patients can enjoy long-term benefit from these treatments, meaning that they are possibly "cured."

Dr. Clarke on Melanoma Biopsies

July 25th 2014

Loren Clarke, MD, vice president of Medical Affairs of Dermatology at Myriad Genetics, discusses melanoma biopsies.

Future Immunotherapy Strategies in Cancer

July 18th 2014

Checkpoint Inhibitors Under Exploration in RCC

July 18th 2014

Return of Interferon in RCC

July 18th 2014

Potential Immunotherapy Combinations in RCC

July 18th 2014

PD-1 Combinations Explored in RCC

July 18th 2014

Immunotherapy Combination Strategies in RCC

July 18th 2014

Sequencing Checkpoint Inhibitors in NSCLC

July 18th 2014

Optimizing Checkpoint Inhibition in NSCLC

July 18th 2014

Immune Checkpoint Inhibitors in NSCLC

July 18th 2014

Evolving Renal Cell Carcinoma Treatment Paradigm

July 18th 2014