Immuno-Oncology | Specialty

Pembrolizumab Demonstrates Potential of Immunotherapy in Gastric Cancer

August 5th 2015

Yung-Jue Bang, MD, PhD, discusses how the results of the KEYNOTE-012 study demonstrate the potential of immunotherapy in treating gastric cancer.

Role of Anti-PD-1/PD-L1 Immunotherapy in Bladder Cancer

August 3rd 2015

Results from clinical trials demonstrate that immunotherapy is ready to take center stage in the fight against bladder cancer.

Immune Checkpoint Combination Strategies Evolving in NSCLC

August 1st 2015

A number of clinical trials are now assessing PD-1 and PD-L1 inhibitors in combination with chemotherapy, targeted therapies, and radiation therapy in an attempt to further improve outcomes for patients with non–small cell lung cancer.

Translational Advances Deliver Precision Medicine to NSCLC

July 31st 2015

Paul Bunn, MD, discussed the latest translational advances in NSCLC at the 2015 International Lung Cancer Congress.

ASCO 2015: All About PD-1, But What's Next?

July 29th 2015

At the 2015 ASCO Annual Meeting, we witnessed an extraordinary explosion into the general oncology consciousness of the Programmed Death-1: Programmed Death Ligand-1 axis and drugs that target that interaction.

Anti-PD-L1 Immunotherapy: Emerging Clinical Data

July 27th 2015

Emerging clinical data suggest that targeted immunotherapy in cancer will become an integral part of the clinical management strategy for solid tumors.

Pembrolizumab Benefit in SCCHN Confirmed in Expansion Study

July 24th 2015

Tanguy Y. Seiwert, MD, discusses the significance of the expansion results of KEYNOTE-012 for advanced squamous cell carcinoma of the head and neck.

Study Adds Pembrolizumab to Paradigm for Certain Head and Neck Cancers

July 24th 2015

A group of researchers at Washington University in St. Louis recently opened a clinical trial to evaluate pembrolizumab as treatment intensification therapy for patients with high-risk locoregionally advanced, previously untreated, HPV-negative head and neck squamous cell carcinomas.

Dr. Luis A. Diaz, Jr. on Pembrolizumab For MMR-Deficient Colorectal Cancer

July 23rd 2015

Luis A. Diaz, Jr. MD, associate professor of Oncology, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, discusses the efficacy of PD-1 inhibitor pembrolizumab (Keytruda) in heavily pretreated colorectal cancer patients with mismatch repair (MMR).

Dr. Infante on Avelumab's Potential in Ovarian Cancer

July 22nd 2015

Jeffrey R. Infante, MD, director, Drug Development Program, Sarah Cannon Research Institute, discusses the potential impact avelumab could have on the treatment of patients with ovarian cancer.

European Commission Approves Pembrolizumab for Advanced Melanoma

July 22nd 2015

The European Commission has approved the PD-1 inhibitor pembrolizumab as a treatment for adult patients with unresectable or metastatic melanoma in the first-line and previously treated settings.

A Focus on Pathways: Evolving Role of Oncolytic Immunotherapy in Melanoma

July 21st 2015

Advances in the field of immunotherapy and targeted therapy have brought about new recommendations for patients with melanoma.

Nivolumab Improves Survival in Phase III RCC Trial

July 20th 2015

The phase III CheckMate-025 trial has been halted after an independent panel determined that nivolumab improved overall survival versus everolimus in patients with advanced renal cell carcinoma.

Dr. Nanda on Immunotherapy in Metastatic TNBC

July 18th 2015

Rita Nanda, MD, assistant professor of Medicine, associate director, Breast Medical Oncology, The University of Chicago Medicine, discusses the efficacy of pembrolizumab and atezolizumab for the treatment of patients with metastatic triple-negative breast cancer.

FDA Grants Peptide Vaccine Orphan Status for Ovarian Cancer

July 17th 2015

The FDA has granted an orphan drug designation to the immunotherapy DPX-Survivac as a treatment for women with ovarian cancer.

Global Perspective on the ASCO Annual Meeting

July 16th 2015

New Agents for Refractory Metastatic Colorectal Cancer

July 16th 2015

Immunotherapy in Colorectal Cancer

July 16th 2015

Maintenance Therapy in Colorectal Cancer

July 16th 2015

EGFR Inhibition in RAS Wild-Type Unresectable mCRC

July 16th 2015