Hematologic Oncology | Specialty

The OncLive Hematology Oncology condition center page is a comprehensive resource for clinical news and expert insights on various hematologic malignancies, including leukemias, lymphomas, myeloproliferative neoplasms, multiple myeloma, and much more. This section features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in hematologic cancers.

CAR T Cells Highly Successful in ALL

October 9th 2017

Defined composition CAR T cells directed against CD19 have potent anti-tumor activity in B cell malignancies, including acute lymphocytic leukemia.

New AML Drugs Approved and Under Investigation in 2017

October 9th 2017

After nearly 40 years with little in the way of drug development for the treatment of acute myeloid leukemia, four new drugs have been approved by the FDA in 2017 for AML, and several promising agents are in development.

Managing Newly-Diagnosed Multiple Myeloma

October 8th 2017

Shaji K. Kumar, MD, discusses proper diagnosis, risk stratification, and personalized medicine for patients with newly-diagnosed multiple myeloma.

Dr. Mesa on Guideline Updates in Polycythemia Vera and Essential Thrombocythemia

October 8th 2017

Ruben Mesa, chair of the Division of Hematology and Medical Oncology at Mayo Clinic, discusses the guideline updates in polycythemia vera and essential thrombocythemia.

Dr. Winter Discusses Response in Follicular Lymphoma

October 8th 2017

Jane N. Winter, MD, professor of medicine, Division of Hematology/Oncology, Northwestern University, discusses response in follicular lymphoma.

New Therapies Being Developed Rapidly for Relapsed Hodgkin Lymphoma

October 8th 2017

In relapsed classical Hodgkin lymphoma, the era of therapies post-brentuximab vedotin is developing rapidly.

Wierda Discusses Novel Combinations, Sequencing in CLL

October 8th 2017

William G. Wierda, MD, PhD, discusses the continued importance of ibrutinib, the promise for novel combinations, and the impact this progress has had on sequencing for CLL.

Data Emerges on Maintenance Therapies, Developing Treatments for Relapsed/Refractory FL

October 8th 2017

Survival for patients with grade 1 to 2 follicular lymphoma is now measured in decades to coincide with improvements in therapy.

Reinduction Regimen Effective in Late Marrow-Relapsed Pediatric ALL

October 6th 2017

In the CALL-0603 study of 44 patients with first marrow-relapsed childhood acute lymphoblastic leukemia, the second complete remission rate was 72.7% for a chemotherapy regimen that included a reduced dose of idarubicin.

Dr. Hofmeister on the Treatment of Patients with Newly Diagnosed Myeloma

October 3rd 2017

Craig Hofmeister, MD, associate professor, The Ohio State University Comprehensive Cancer Center, discusses the treatment of patients with newly diagnosed multiple myeloma.

Dr. Awan Discusses Venetoclax in CLL

October 3rd 2017

Farrukh Awan, MBBS, associate professor, The Ohio State University Comprehensive Cancer Center, discusses venetoclax (Venclexta) in chronic lymphocytic leukemia.

Japan Approves Daratumumab for Relapsed/Refractory Myeloma

October 3rd 2017

The Japanese Ministry of Health, Labor and Welfare has approved the use of daratumumab (Darzalex) for the treatment of adults with relapsed/refractory multiple myeloma.

Brentuximab Vedotin Receives Breakthrough Therapy Designation for Frontline Hodgkin Lymphoma

October 2nd 2017

The FDA has awarded brentuximab vedotin (Adcetris) a breakthrough therapy designation for the first-line treatment of patients with classical Hodgkin lymphoma.

Penn Seeks to Make CAR T-Cell Therapy Work in Solid Tumor Disease

September 30th 2017

Chimeric antigen receptor T-cell therapy for hematological malignancies took a huge step forward this summer with the FDA approval of Novartis

Expert Weighs in on Recent AML Advances

September 28th 2017

Harry Erba, MD, PhD, reflects on the 4 approvals and their effect on the treatment of AML moving forward.

Managing Thromboembolic Events in Pediatric Cancer

September 23rd 2017

Guy Young, MD, discussed the use of anticoagulants in managing thromboembolic events in pediatric cancer.

High Response Rate, MRD Negativity Confirmed for Venetoclax in CLL

September 22nd 2017

Treatment with the BCL-2 inhibitor venetoclax (Venclexta) led to negative minimal residual disease (MRD) status in 40% of evaluable patients with relapsed/refractory chronic lymphocytic leukemia.

Observation After Diagnosis Viable Strategy for Some Patients With MCL

September 21st 2017

Some patients with mantle cell lymphoma can delay treatment without experiencing negative outcomes, according to findings from a population-based study.

Dr. Young Discusses Thromboembolic Events in Pediatric Cancer

September 21st 2017

Guy Young, MD, director, Hemostasis and Thrombosis Program, attending physician, Hematology, Oncology and Blood and Marrow Transplantation, Children’s Hospital Los Angeles, USC, discusses the occurrence of thromboembolic events in pediatric cancer.

Update Sustains Tisagenlecleucel Activity in Pediatric ALL

September 20th 2017

Tisagenlecleucel (Kymriah) induced a complete remission with complete or incomplete hematologic recovery in 83% of pediatric, adolescent, and young adult patients with acute lymphoblastic lymphoma.