Head & Neck Cancers | Specialty

The OncLive Head and Neck Cancer condition center page is a comprehensive resource for clinical news and expert insights on treatment for patients with head and neck cancer. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research within head and neck cancer.

Dr. Machiels on Pembrolizumab in Head and Neck Cancer

June 23rd 2017

Jean-Pascal Machiels, MD, head of the Department of Medical Oncology, Cliniques Universitaires Sain-Luc, discusses pembrolizumab (Keytruda) in patients with head and neck cancer.

Dr. Ferris on Combining Immunotherapy and Radiation Therapy in Head and Neck Cancer

June 22nd 2017

Robert Ferris, MD, PhD, vice chair for Clinical Operations, associate director for Translational Research, and co-leader of the Cancer Immunology Program at the University of Pittsburgh Cancer Institute, discusses the rationale for combining radiation therapy with immunotherapy for the treatment of patients with head and neck cancer.

Dr. Machiels on Toxicities with Pembrolizumab for Head and Neck Cancer

June 20th 2017

Jean-Pascal Machiels, MD, head of the Department of Medical Oncology, Cliniques Universitaires Sain-Luc, discusses toxicities with pembrolizumab (Keytruda) in combination with chemoradiation for patients with head and neck cancer.

Dr. Lee on Combining Anti-PD-L1 to Standard of Care for Head and Neck Cancer

June 20th 2017

Nancy Y. Lee, MD, vice chair, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, discusses the combination of a PD-L1 inhibitor to the standard of care for patients with head and neck cancer.

Dr. Ferris on Immunotherapy in Locally Advanced Head and Neck Cancer

June 19th 2017

Robert Ferris, MD, PhD, vice chair for Clinical Operations, associate director for Translational Research, and co-leader of the Cancer Immunology Program at the University of Pittsburgh Cancer Institute, discusses immunotherapy in patients with locally advanced head and neck cancer.

Lenvatinib Significantly Extends OS in Older Patients With Thyroid Cancer

June 19th 2017

Lenvatinib (Lenvima) significantly improved overall survival in patients older than 65 years with radioiodine-refractory differentiated thyroid cancer.

Dr. Machiels on Ongoing Trial of Pembrolizumab Plus Chemoradiation in HNSCC

June 14th 2017

Jean-Pascal Machiels, MD, head of the Department of Medical Oncology, Cliniques Universitaires Sain-Luc, discusses an ongoing clinical trial of pembrolizumab (Keytruda) combined with chemoradiation in patients with locally advanced head and neck squamous cell carcinoma (HNSCC).

Dr. Lee on the Impact of Immunotherapy in Head and Neck Cancer

June 14th 2017

Nancy Y. Lee, MD, vice chair, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, discusses the impact of immunotherapy in head and neck cancer.

Dr. Ferris Discusses the RTOG 3504 Study in Head and Neck Cancer

June 13th 2017

Robert Ferris, MD, PhD, vice chair for Clinical Operations, associate director for Translational Research, and co-leader of the Cancer Immunology Program at the University of Pittsburgh Cancer Institute discusses the RTOG 3504 study in head and neck cancer.

Epacadostat/ Nivolumab Shows Promising Efficacy for Melanoma, Head and Neck Cancer

June 6th 2017

The combination of the IDO inhibitor epacadostat and nivolumab demonstrated promising signs of activity for patients with squamous cell carcinoma of the head and neck and those with melanoma.

Analysis Finds Similar Efficacy Between Chemoradiation Regimens in SCCHN

June 1st 2017

An analysis in locally advanced squamous cell carcinoma of the head and neck showed that weekly low-dose schedules of chemoradiotherapy produce comparable survival outcomes and response rates as the standard 3-weekly schedule.

The Detection of Galectin-1 in Head and Neck Cancer

May 29th 2017

Dhanya K. Nambiar, PhD, Stanford University, discusses the detection of Galectin-1 for patients with head and neck cancer.

Study Reclassifies HPV-Positive Head and Neck Cancer

May 26th 2017

Iain Morgan, PhD, discusses research that redefines HPV-positive head and neck cancer and may also identify new therapeutic targets.

The Development of Galectin-1 for Head and Neck Cancer

May 24th 2017

Dhanya K. Nambiar, PhD, Stanford University, discusses the importance of continuing to study Galectin-1 for patients with head and neck cancer.

Future of Immunotherapy in Head and Neck Cancer May Be in Combinations

May 22nd 2017

Researchers are hoping to build on the success of the KEYNOTE-012 and CheckMate-141 trials, which led to the approvals of pembrolizumab and nivolumab, respectively, by examining anti–PD-1/PD-L1 agents in the frontline and as a part of combination regimens for patients with head and neck cancer.

Study Spotlights Patient Difficulties When Opting Against Thyroid Cancer Treatment

May 19th 2017

Louise Davies, MD, discusses the experience of patients with incidentally identified thyroid cancer who choose to not receive treatment.

Dr. Papa on Leukapheresis Manufacturing Approach in Head and Neck Cancer

May 18th 2017

Sophie Papa, PhD, MBBS, MRCP, medical oncologist, Clinical Academic Group, Department of Research Oncology, King’s College London, discusses leukapheresis manufacturing approach in head and neck cancer.

Experts Respond to USPSTF Recommendation Against Thyroid Cancer Screening

May 11th 2017

The US Preventive Services Task Force announced that it recommends against screening for thyroid cancer in asymptomatic adults.

PD-L1 Expression Strongly Associated With Radiation Resistance in HPV-Negative HNSCC

May 11th 2017

High PD-L1 expression is closely associated with local failure following radiotherapy in HPV-negative head and neck squamous cell carcinomas, according to recent study.

Emerging Therapies Show Promise in Head and Neck Cancer

May 4th 2017

Aarti Bhatia, MD, highlights the newer single agents and combination treatments being investigated for patients with head and neck cancer.