Head & Neck Cancers | Specialty

Rolling Submission for Toripalimab Started for Nasopharyngeal Carcinoma

March 4th 2021

The filing of a biologics license application has been initiated with the FDA for toripalimab for the treatment of patients with recurrent or metastatic nasopharyngeal carcinoma.

FDA Grants Breakthrough Therapy Designation to Tipifarnib for HRAS-Mutated HNSCC

February 24th 2021

February 24, 2021 - The FDA has granted a breakthrough therapy designation to tipifarnib for use in patients with recurrent or metastatic HRAS-mutated head and neck squamous cell carcinoma with variant allele frequency of 20% or higher following progressive disease on platinum-based chemotherapy.

Investigators Aim Novel T-Cell Therapy at Solid Tumor Target

February 23rd 2021

ADP-A2M4CD8, a novel T-cell therapy, is being investigated in a range of tumor types that express MAGEA4, an antigen expressed in solid tumors that investigators say represents a promising target for cellular immunotherapy.

Treating BRAF V600 and NTRK Gene Fusion Positivity

February 11th 2021

The Future of RAI-Refractory DTC Management

February 11th 2021

Frontline Durvalumab Fails to Improve OS in Recurrent or Metastatic HNSCC

February 5th 2021

February 5, 2021 - Durvalumab failed to improve overall survival over the EXTREME chemotherapy regimen in the frontline treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma with tumors expressed high levels of PD-L1, missing a primary end point of the phase 3 KESTREL trial.

Rationale for Sequencing in Second Line

February 4th 2021

LIBRETTO-001 Phase 1/2 Trial Overview

February 4th 2021

Advice for Managing RAI-Refractory DTC

January 28th 2021

Molecular Testing in Treatment Selection

January 28th 2021

Search Continues for Agents to Provide Additive Benefit to Chemoradiation in Head and Neck Cancer

January 21st 2021

Nabil F. Saba, MD, FACP, discusses the results of the JAVELIN Head and Neck 100 trial, as well as data from other key, recent studies in head and neck cancer.

Sorafenib and Lenvatinib Side Effect Profile and Dosing

January 21st 2021

RAI-Refractory DTC Trials: Phase 3 DECISION and SELECT

January 21st 2021

28-Gene Score May Predict Distant Metastatic Recurrence in Advanced Head and Neck Cancers

January 18th 2021

Although the ability to treat head and neck cancer has certainly improved over the years, a significant percentage of patients experience recurrent disease after initial treatment.

Multidisciplinary Management for the Treatment of DTC

January 18th 2021

Approaching Treatment of Low-Volume DTC

January 18th 2021

Understanding Sequencing and What to Look for in DTC

January 18th 2021

Roles and Communication in Treatment in DTC

January 11th 2021

Management of DTC in Clinical Practice

January 11th 2021

NICE Rejects Nivolumab for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

January 8th 2021

January 8th, 2021 - The United Kingdom’s National Institute for Health and Care Excellence has issued guidelines recommending against nivolumab for use in patients with recurrent or metastatic head and neck squamous cell carcinoma who experienced disease progression during or after platinum-based chemotherapy.