Gynecologic Oncology | Specialty

The OncLive Gynecologic Oncology condition center page is a comprehensive resource for clinical news and expert insights on various types of gynecologic cancers, including ovarian cancer, endometrial cancer, and uterine cancer, among others. This section features news articles, interviews with gynecologic oncologists in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in gynecologic cancers.

Immunotherapy and You: Understanding the PD-L1 Blockade

November 23rd 2022

In this fifth episode of OncChats: Immunotherapy and You, John Nakayama, MD, and Ali Amjad, MD, discuss PD-1 blockade, potential biomarkers of response to treatment with immunotherapy, and the potential for these agents in the neoadjuvant setting.

Dr. Salani on the Role of HER2 Expression in Advanced Uterine Serous Carcinoma

November 22nd 2022

Ritu Salani, MD, MBA, discusses the role of HER2 expression on treatment decisions in advanced uterine serous carcinomas.

European Commission Approves Cemiplimab for Recurrent or Metastatic Cervical Cancer

November 22nd 2022

The European Commission has approved cemiplimab-rwlc monotherapy for the treatment of adult patients with recurrent or metastatic cervical cancer who have progressed on or after platinum-based chemotherapy.

Fertility and Other Treatment Considerations for Patients With Advanced Endometrial Cancer

November 22nd 2022

The panel shares how they determine a treatment regimen for patients with advanced endometrial cancer taking into consideration fertility and family planning, hereditary conditions, and comorbidities.

Patient Profile Presentation: A 76-Year-Old Woman With Advanced Endometrial Cancer

November 22nd 2022

Kathleen Lutz, RN, NP-BC WH, presents a 76-year-old woman with advanced endometrial cancer, and the panel assesses the chosen treatment regimens.

Crane Helps Gynecologic Fellows Deliver Care in a Complicated Time

November 21st 2022

Dr Crane discusses why Atrium Health decided to launch a gyn onc fellowship, how she helps fellows navigate the current political landscape while maintaining high-level care, and how she tries to model a good work-life balance for her trainees.

Onatasertib Plus Toripalimab Elicits Early Responses in Relapsed/Metastatic Cervical Cancer

November 17th 2022

Onatasertib plus toripalimab elicited an objective response rate of 52.4% in patients with relapsed or metastatic cervical cancer, irrespective of PD-L1 expression.

Long-term Survival Data With Immunotherapy in Gynecologic Cancers

November 16th 2022

In this fourth episode of OncChats: Immunotherapy and You, John Nakayama, MD, and Ali Amjad, MD, highlight long-term survival data reported with immunotherapy approaches in patients with gynecologic cancers.

Dr. Binder on the Use of Immune Checkpoint Inhibitors in Endometrial Cancer Treatment

November 16th 2022

Pratibha Binder, MD, discusses how the introduction of novel immune checkpoint inhibitors into frontline treatment strategies could ameliorate unmet needs in endometrial cancer.

Dr. Salani on Updates in Treating Endometrial Cancer

November 15th 2022

Ritu Salani, MD, MBA, discusses updates in treating endometrial cancer.

Dr. Matulonis on the FDA Approval of Mirvetuximab Soravtansine in Frα+ Platinum-resistant Ovarian Cancer

November 15th 2022

Ursula A. Matulonis, MD, discusses the significance of the FDA approval of mirvetuximab soravtansine-gynx in patients with folate receptor α–positive, platinum-resistant ovarian cancer.

FDA Approves Mirvetuximab Soravtansine-gynx for FRα+ Platinum-resistant Ovarian Cancer

November 14th 2022

The FDA has granted accelerated approval to mirvetuximab soravtansine-gynx (Elahere) for the treatment of select patients with folate receptor α–positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer.

Dr. Saenz on the Need for Ongoing Research Efforts in Cervical Cancer

November 14th 2022

Cheryl Saenz, MD, discusses the need for ongoing research efforts in cervical cancer.

FDA Requests Restriction of Second-line Maintenance Niraparib Indication in Ovarian Cancer

November 14th 2022

At the request of the FDA, GlaxoSmithKline plc will restrict the second-line maintenance indication for niraparib to only the population of patients with recurrent ovarian cancer whose tumors harbor deleterious or suspected deleterious germline BRCA mutations.

PARP Maintenance Therapy Provides Varying Benefit in Advanced Ovarian Cancer

November 10th 2022

The benefit of PARP maintenance therapy for patients with advanced ovarian cancer differs depending on a number of factors, including the homologous recombination and BRCA mutation status of the tumor.

Immunotherapy and You: The 5 Cs in Gynecologic Cancer

November 9th 2022

In this third episode of OncChats: Immunotherapy and You, John Nakayama, MD, and Ali Amjad, MD, review the 5 C's to consider when conducting research in gynecologic cancers and beyond.

40th Annual CFS® Highlights New Frontiers in Cancer Care

November 9th 2022

The Chemotherapy Foundation Symposium® returns to New York City for its 40th annual meeting with a 3-day program that will deliver the latest updates across the gamut of oncology care.

Dr. Binder on Key Trials Improving the Treatment Landscape for Endometrial Cancer

November 3rd 2022

Pratibha Binder, MD, discusses key trials improving the array of treatment options for patients with endometrial cancer.

Immunotherapy and You: Gynecologic Treatment Efficacy From a Patient’s Perspective

November 2nd 2022

In this second episode of OncChats: Immunotherapy and You, John Nakayama, MD, and Ali Amjad, MD, discuss the safety and efficacy of immunotherapy vs standard chemotherapy in patients with gynecologic cancers.

Unmet Needs and Clinical Pearls for Metastatic Endometrial Cancer

November 1st 2022

Before closing out their conversation on endometrial cancer, Kathleen Moore and David O’Malley summarize unmet needs in the field and share a few clinical pearls on managing patients with the disease.