Genitourinary Cancers | Specialty

The OncLive Genitourinary Cancer condition center page is a comprehensive resource for clinical news and expert insights across genitourinary (GU) malignancies, including renal cell carcinoma, urothelial carcinoma, and prostate cancer. This section features news articles, interviews in written and video format, and podcasts that focus on the evolving treatment paradigm of GU cancers and emerging research.

Tailored Therapy Approaches for Upfront mRCC Treatment

July 23rd 2020

Treating Side Effects of Therapy for mRCC with Steroids

July 23rd 2020

Evaluating Safety Profiles of Upfront Regimens for mRCC

July 23rd 2020

Choosing Upfront Therapy for mRCC

July 23rd 2020

CheckMate 9ER: Phase 3 Trial of Frontline Nivolumab + Cabozantinib

July 23rd 2020

Evaluating Long-Term Follow-Up Data for Treatment of mRCC

July 23rd 2020

Patient Factor Consideration for Treatment of mRCC

July 23rd 2020

Applying Clinical Trial Data for Treatment of mRCC

July 23rd 2020

Clinical Trials Defining the NCCN Guidelines for Frontline Treatment of mRCC

July 23rd 2020

Evaluation of Risk for Frontline Advanced/Metastatic Clear Cell RCC

July 23rd 2020

UGN-102 Emerges As Potential Surgical Alternative for Low-Grade, Intermediate-Risk NMIBC

July 18th 2020

Primary chemoablation with UGN-102 elicited encouraging responses in patients with low-grade, intermediate-risk non–muscle-invasive bladder cancer and may consequently be an appropriate nonsurgical treatment intervention for patients.

Cytoreductive Nephrectomy Retains Role in mRCC in the Immune Checkpoint Inhibitor Era

July 13th 2020

Ziad Bakouny, MD, MSc, discusses the controversy behind the use of cytoreductive nephrectomy in metastatic renal cell carcinoma, factors to consider when selecting patients for this approach, and ongoing trials examining remaining questions in the field.

Rini Reviews Key ASCO 2020 Highlights in Genitourinary Cancers

July 13th 2020

As part of the 2020 ASCO Direct Highlights™ webcast, Brian Rini, MD, discusses key developments in genitourinary cancers that were presented during the 2020 ASCO Virtual Scientific Program.

Survey Indicates Urgent Need For COVID-19 Testing in Vulnerable Patients With Kidney Cancer

July 9th 2020

Only a small percentage of patients with kidney cancer who are considered to be particularly vulnerable to COVID-19 have actually been tested for infection.

Long-Term KEYNOTE-426 Data Support Pembrolizumab/Axitinib as Frontline Standard in Advanced RCC

July 9th 2020

Pembrolizumab plus axitinib continued to significantly improve efficacy over sunitinib in patients with previously untreated metastatic renal cell carcinoma, according to updated results from the phase 3 KEYNOTE-426 trial.

Dr. Jonasch on the Safety Profile of MK-6482 in Von Hippel-Lindau Disease–Associated RCC

July 8th 2020

Eric Jonasch, MD, discusses the safety profile of the investigational oral hypoxia-inducible factor-2α inhibitor MK-6482 in Von Hippel-Lindau disease–associated renal cell carcinoma.

MK-6482 Showcases Promising Clinical Activity in VHL Disease–Associated RCC

July 8th 2020

Eric Jonasch, MD, on the favorable efficacy and tolerability of MK-6482 in patients with Von Hippel-Lindau disease–associated renal cell carcinoma.

FDA Approves Avelumab as Frontline Maintenance in Metastatic Urothelial Carcinoma

July 1st 2020

The FDA has approved avelumab (Bavencio) for the maintenance treatment of patients with locally advanced or metastatic urothelial carcinoma that has not progressed with first-line platinum-based chemotherapy.

Dr. McKay on the Design of the PDIGREE Trial in Advanced RCC

June 25th 2020

Rana R. McKay, MD, discusses the design of the phase 3 PDIGREE study in advanced renal cell carcinoma.

Dr. Ramos on the Role of BCG In Non-Muscle Invasive Bladder Cancer

June 25th 2020

Félix Guerrero-Ramos, MD, PhD, FEBU, discusses the role of Bacillus Calmette-Guerin in the treatment of patients with non-muscle invasive bladder cancer.