Gastrointestinal Cancer | Specialty

The OncLive Gastrointestinal Cancer condition center page is a comprehensive resource for clinical news and expert insights on various types of gastrointestinal (GI) cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, colorectal cancer, cholangiocarcinoma, esophageal cancer, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in GI cancers.

PARP Inhibitors May Help Fight Colon Cancer

April 28th 2011

A class of drugs that has shown encouraging results in breast and ovarian cancers with BRCA gene mutations may also benefit patients who have colorectal cancers

Sunitinib Becomes 2nd Pancreatic Cancer Drug to Gain FDA Panel's Support

April 13th 2011

Pfizer's sunitinib provides a favorable benefit-risk profile in patients with unresectable pancreatic neuroendocrine tumors (pNETs)

FDA Panel Unanimously Supports Use of Everolimus in Pancreatic Cancer

April 12th 2011

After much anticipation the Oncologic Drugs Advisory Committee has returned a verdict on Novartis' everolimus (Afinitor)

Chasing a Breakthrough in Cancer Cell Signaling: An Interview With William G. Cance, MD

March 29th 2011

In 1993, William G. Cance, MD, was the first researcher to clone human focal adhesion kinase (FAK) and demonstrate its overexpression in metastatic cancers.

The Use of Tyrosine Kinase Inhibitors for Gastrointestinal Stromal Tumors (GIST)

March 15th 2011

In this review article, the author discusses the use of tyrosine kinase inhibitors in the management of patients with gastrointestinal stromal tumors.

ASCO GI Coverage: Delaying Chemotherapy Increases the Mortality Risk of Patients with Colon Cancer

March 14th 2011

The results of a systematic review and meta-analysis suggest that the mortality risk for colon cancer patients begins to increase with any avoidable delay in adjuvant chemotherapy beyond 4 weeks.

ASCO GI Coverage: Everolimus Associated With Significant PFS Improvement in Patients With PNETs

March 13th 2011

Data from a large randomized trial showed that treatment with the targeted agent everolimus was associated with a 65% improvement in progression-free survival (PFS) in patients with advanced pancreatic neuroendocrine tumors (PNETs).

Laura Metcalfe on Colorectal Screening

March 12th 2011

Laura Metcalfe, MSN, RN, APN, C, AOCNS Advanced Practice Nurse, GI Division from John Theurer Cancer Center on Colorectal Screening

Laura Metcalfe on the Virtual Colonoscopy

March 12th 2011

Laura Metcalfe, MSN, RN, APN, C, AOCNS Advanced Practice Nurse, GI Division from John Theurer Cancer Center on the Virtual Colonoscopy

Net Guides: Renal Cell Carcinoma

March 10th 2011

Useful Online Resources and Clinical Trials for Renal Cell Carcinoma

Technology for the Taking at Research Hub in Scotland

March 9th 2011

The University of Glasgow will begin offering medical and scientific research findings, including cancer-related discoveries, to businesses and entrepreneurs free of charge

FDA Green-Lights Phase III Trial for Drug-Eluting Microspheres in Liver Cancer

March 9th 2011

The FDA has given Merit Medical Systems the green light for a phase III clinical trial investigating QuadraSphere Microspheres in patients with primary liver cancer.

FDA Considers Approval of Fusilev for Colorectal Cancer

March 9th 2011

The FDA has notified Spectrum Pharmaceuticals that it will decide whether to approve Fusilev (levoleucovorin) for colorectal cancer within 6 months.

Net Guides: Colon Cancer

March 8th 2011

Useful Online Resources and Clinical Trials for Colon Cancer

Net Guides: Liver Cancer

March 7th 2011

Useful Online Resources and Clinical Trials for Liver Cancer

Net Guides: Gastrointestinal Cancers

March 6th 2011

Useful Online Resources and Clinical Trials for Gastrointestinal Cancers

2011 Gastrointestinal Cancers Symposium

March 6th 2011

ColoPrint, a microarray-based gene signature test, accurately identifi ed the risk of recurrence of colorectal cancer in patients with localized stage II disease, raising the potential of an exciting new prognostic tool for clinicians.

John Theurer Cancer Center Opens New Comprehensive Facility

March 4th 2011

The John Theurer Cancer Center (JTCC) at Hackensack University Medical Center in New Jersey, one of the largest cancer centers in the United States

Interview With Siddhartha Mukherjee, Author of The Emperor of All Maladies

March 4th 2011

Siddhartha Mukherjee, MD, discusses his book The Emperor of All Maladies.

Avastin Alarm

March 4th 2011

A meta-analysis of randomized controlled trials revealed treatment-related fatalities were 1.5 times higher for combination treatment with Avastin (bevacizumab) and chemotherapy versus chemotherapy alone