Gastrointestinal Cancer | Specialty

Optimizing Frontline Chemotherapy in mCRC

February 12th 2016

FOLFOX versus FOLFIRI in the MAVERICC Trial in CRC

February 12th 2016

Systemic Therapy Approaches in mCRC

February 12th 2016

Immunotherapy and MSI Status in Colorectal Cancer

February 12th 2016

Molecular Profiling in Colorectal Cancer

February 12th 2016

Liver-Directed Therapies in Metastatic Colorectal Cancer

February 12th 2016

Metastatic Colorectal Cancer: Goals of Resection

February 12th 2016

Taking a Multidisciplinary Approach to mCRC Care

February 12th 2016

First-in-Class Drug Targets Stem Cells in Gastric Cancer Trial

February 11th 2016

Manish A. Shah, MD, discusses the BRIGHTER trial, which is investigated BBI608 as a second-line treatment for patients with gastric and gastroesophageal junction cancer who already have undergone platinum and fluoropyrimidine-based chemotherapy.

Patient Populations Provide Sequencing Clues in Chemorefractory CRC

February 11th 2016

Treating patients with chemorefractory advanced colorectal cancer has undergone a significant transformation in recent years. Now, with two agents approved, the optimal sequence for therapies regorafenib and TAS-102 becomes the next relevant question.

Dr. Eng on Emerging Agents for Treatment of Anal Cancer

February 8th 2016

Cathy Eng, MD, FACP, professor, director, Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, Network Clinical Research, associate medical director, Colorectal Center, University of Texas MD Anderson Cancer Center, discusses emerging agents for the treatment of patients with anal cancer.

Liver-Directed Therapy for Hepatic Malignancies

February 8th 2016

Management of hepatic malignancies requires a multidisciplinary approach, and is based on the tumor burden, liver function, and PS of the patient.

Second-Line Treatment Feasible, Beneficial After Upfront Nab-Paclitaxel in Pancreatic Cancer

February 2nd 2016

Second-line treatment of metastatic pancreatic cancer proved to be feasible and beneficial, particularly for patients who received nab-paclitaxel in addition to gemcitabine in the first-line setting.

PFS in Metastatic Colorectal Cancer Similar with Two Chemo Backbones

January 26th 2016

A potential biomarker to guide chemotherapy for metastatic colorectal cancer failed to stratify patients by progression-free survival or responsiveness to bevacizumab.

Dr. Kunz on the CLARINET Study for GEP-NETs

January 26th 2016

Pamela L. Kunz, MD, assistant professor, Division of Oncology, Stanford University School of Medicine, discusses tumor response in the CLARINET study, which examined lanreotide depot versus placebo in patients with metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

Three Drugs Marginally Better Than Two in First-Line Metastatic Colorectal Cancer

January 25th 2016

Patients with metastatic colorectal cancer (mCRC) had marginal yet inconsistent improvement in clinical outcomes when treated with a three-drug chemotherapy regimen plus bevacizumab compared with a doublet-bevacizumab regimen.

Panitumumab Improves Survival in Chemorefractory mCRC

January 25th 2016

Adding panitumumab (Vectibix) to best supportive care reduced the risk of death by 30% for patients with RAS wild-type chemorefractory metastatic colorectal cancer.

Neoadjuvant Carboplatin/Paclitaxel Showing Potential in Esophageal Cancer

January 25th 2016

Neoadjuvant treatment with carboplatin and paclitaxel-based chemotherapy produced a 27.9% pathologic complete response rate in patients with resectable esophageal cancer, according to results of the NEOSCOPE trial.

Avelumab Clinically Active in Advanced Gastric/GEJ Cancer

January 23rd 2016

The investigational anti–PD-L1 antibody avelumab demonstrated clinical activity as a second-line and maintenance therapy for patients with unresectable gastric or gastroesophageal junction cancer.

Dr. Shahda on BBI-608 With Gemcitabine and Nab-Paclitaxel in Patients with mPDAC

January 23rd 2016

Safi Shahda, MD, assistant professor of Clinical Medicine, Indiana University School of Medicine, discusses a phase Ib study examining the cancer stem cell pathway inhibitor BBI-608 in combination with gemcitabine and nab-paclitaxel in patients with metastatic pancreatic ductal adenocarcinoma.