Colorectal Cancer | Specialty

The OncLive Colorectal Cancer condition center page is a comprehensive resource for clinical news and expert insights on colorectal cancer treatment and management, with a focus on novel therapeutic strategies including checkpoint inhibitors and TKIs across lines of therapy. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in colorectal cancer.

Dr. O'Neil on Stemness Inhibitors for CRC Treatment

March 17th 2017

Bert O’Neil, MD, the Joseph W. and Jackie J. Cusick Professor of Oncology, professor of Medicine, and director of the Phase I and Gastrointestinal Oncology Programs at Indiana University, discusses the potential for stemness inhibitors as a treatment for patients with metastatic colorectal cancer (mCRC).

Novel Approaches, Individualization Needed in mCRC

March 16th 2017

Bert O'Neil, MD, discusses the need for novel treatments for patients with metastatic colorectal cancer as well as why researchers need to develop a deeper understanding of tumor biology.

FDA Review Continues for Pembrolizumab in MSI-H Cancer

March 10th 2017

A supplemental biologics license application for pembrolizumab (Keytruda) for previously treated patients with advanced microsatellite instability-high cancer remains under review by the FDA.

Mutations May Help Explain Sidedness Issue in Colorectal Cancer

March 6th 2017

Arturo Loaiza-Bonilla, MD, discusses the potential role of BRAF and CTNNB1 mutations in the survival difference between colorectal cancer patients with left- and right-sided tumors.

Bekaii-Saab Discusses Sequencing and Emerging Combinations in mCRC

March 4th 2017

Tanios Bekaii-Saab, MD, discusses optimal sequencing with regorafenib (Stivarga) and TAS-102 (Lonsurf) in relapsed patients with metastatic colorectal cancer and combination regimens on the rise in the setting.

Interventional Radiology Improving Outcomes in Liver-Metastatic CRC

March 3rd 2017

Rahmi Oklu, MD, PhD, discusses various approaches physicians use to treat patients who have CRC with liver metastases.

First-Line mCRC Treatment Must Encompass Individualized Approach

March 2nd 2017

Axel Grothey, MD, discusses frontline therapy and maintenance strategies for patients with metastatic colorectal cancer.

Dr. Bekaii-Saab on Expanding Landscape in CRC

March 1st 2017

Tanios Bekaii-Saab, MD, professor of Medicine, Mayo Clinic, discusses the expanding treatment landscape of colorectal cancer (CRC).

Dr. Grothey on Treatment Landscape of mCRC

February 28th 2017

Axel Grothey, MD, medical oncologist, Mayo Clinic, discusses some of the therapeutic approaches in the field of metastatic colorectal cancer (CRC).

Ongoing Clinical Trials in Colorectal Cancer

February 10th 2017

Broad Molecular Profiling in Colorectal Cancer

February 10th 2017

Survivorship Care Plans in Colorectal Cancer

February 10th 2017

Colorectal Cancer: Dosing Strategies With Regorafenib

February 10th 2017

Trifluridine/Tipiracil in Advanced Colorectal Cancer

February 10th 2017

Setting Expectations in Third-Line Colorectal Cancer

February 10th 2017

Long-Term Therapeutic Strategies in Colorectal Cancer

February 10th 2017

Selective Internal Radiation Therapy in Colorectal Cancer

February 10th 2017

Intrahepatic Radiation in Colorectal Cancer

February 10th 2017

Management of Liver-Dominant Unresectable Colorectal Cancer

February 10th 2017

Neoadjuvant/Adjuvant Approaches in Colorectal Cancer

February 10th 2017