Colorectal Cancer | Specialty

The OncLive Colorectal Cancer condition center page is a comprehensive resource for clinical news and expert insights on colorectal cancer treatment and management, with a focus on novel therapeutic strategies including checkpoint inhibitors and TKIs across lines of therapy. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in colorectal cancer.

Bevacizumab Plus Second-Line Chemotherapy Extends Survival in Advanced Colorectal Cancer Patients

June 3rd 2012

Bevacizumab plus chemotherapy as a second-line treatment for metastatic colorectal cancer improved survival among patients whose disease had progressed after first-line combination therapy with bevacizumab.

Surgery for Colorectal Cancer Hepatic Metastases Has Little Effect on Health

May 25th 2012

Liver surgery for colorectal cancer hepatic metastases has, for the most part, a minimal and brief negative impact on patient-reported outcomes.

NCCN 17th Annual Conference: Clinical Practice Guidelines & Quality Cancer Care

May 23rd 2012

At this year's annual NCCN conference, the organization presented updates in 13 areas, including specific disease states and general screening methods.

Colonoscopy Recommendation May Cut Adherence to CRC Screening

May 18th 2012

Patients are less likely to complete colorectal cancer screening if their physician recommended colonoscopy rather than recommending fecal occult blood testing.

All Patients With Colorectal Cancer Should Be Genetically Screened

May 7th 2012

Universal tumor testing and a detailed personal and family history assessment are recommended for all patients with newly diagnosed colorectal cancer.

Brivanib Plus Cetuximab Delivers Mixed Results in Colorectal Study

April 16th 2012

Adding brivanib alaninate to cetuximab had no survival advantage over cetuximab alone in patients with KRAS wild-type chemorefractory metastatic colorectal cancer.

Research Backs Anti-EGFR Therapy in mCRC With Wild-Type KRAS

April 13th 2012

New research on predictive and prognostic biomarkers for therapy targeting EGFR strongly suggests that panitumumab should be reserved for mCRC tumors with wild-type KRAS.

Addition of Oxaliplatin to Adjuvant Therapy for Late-Stage Colon Cancer Shows Benefit in Real-World Setting

April 13th 2012

Adding oxaliplatin to conventional chemotherapy increases survival in patients with advanced colon cancer in a broad range of community practice settings.

Many Patients Continue to Smoke After Cancer Diagnosis

April 11th 2012

Being newly diagnosed with lung or colorectal cancer is often not sufficient to motivate cigarette smokers to quit.

Adjuvant Cetuximab Fails to Improve Survival in Colon Cancer

April 3rd 2012

Patients who received cetuximab in combination with a standard adjuvant therapy treatment for colon cancer did not experience improved survival.

Regorafenib Potential Treatment for Metastatic Colorectal Cancer Failing Standard Treatment Options

March 28th 2012

For patients with metastatic colorectal cancer that has progressed on multiple lines of standard therapy, regorafenib may be a new treatment option that achieves disease control.

Prediagnostic Obesity Curbs Colorectal Cancer Survival

March 27th 2012

Patients who are obese before being diagnosed with colorectal cancer are more likely to die of their disease than patients who are at a normal weight prediagnosis.

Baseline Glucose Levels in Older Women May Be Linked to Colorectal Cancer Risk

February 29th 2012

New findings suggest that increased serum glucose levels may be a risk factor for colorectal cancer in postmenopausal women.

Lower Rate of Colorectal Cancer Screening May Be Linked to Higher Cancer Fatalism

January 19th 2012

Higher cancer fatalism, a term that refers to the belief that a cancer diagnosis leads inevitably to death, may be associated with a lower rate of colorectal cancer screening.

Men With Colorectal Cancer Often Not Consulted About Risks for Erectile Dysfunction

January 17th 2012

Men with colorectal cancer are not routinely informed about the potential for erectile dysfunction or how the condition can best be managed.

Prediagnosis Primary Care Visits Improve Outcomes in Medicare Patients With Colorectal Cancer

January 16th 2012

Medicare beneficiaries with CRC who made a higher number of visits to their PCP before their diagnosis had lower disease-related mortality and lower all-cause mortality.

Dr. Chan Discusses the VEGF-Trap Agent Aflibercept

January 13th 2012

Dr. Emily Chan, from Vanderbilt-Ingram Cancer Center, Discusses the VEGF-Trap Agent Aflibercept

Colorectal Tumor Marker: Molecular Evaluation Sheds Light on Negative Lymph Node Status

December 5th 2011

The presence or absence of lymph node involvement has long been recognized as a critically relevant prognostic factor in solid tumor oncology.

Dr. Chan on the Adjuvant Colorectal NO147 Trial

November 30th 2011

Dr. Emily Chan from Vanderbilt-Ingram Cancer Center Discusses the Adjuvant Colorectal NO147 Trial

Dr. Grothey Discusses Novel Agents for Colorectal Cancer

November 11th 2011

Dr. Axel Grothey from the Mayo Clinic Discusses Novel Agents for Colorectal Cancer