Chronic Lymphocytic Leukemia | Specialty

The OncLive Chronic Lymphocytic Leukemia condition center page is a comprehensive resource for clinical news and expert insights on treatment advances and ongoing research in chronic lymphocytic leukemia. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs and updates with chronic lymphocytic leukemia therapy.

Translating Novel CLL Therapies to Other Types of NHL

January 16th 2015

Indolent Non-Hodgkin's Lymphoma Treatment Selection

January 16th 2015

Assessing Response With Novel Agents in CLL

January 16th 2015

Role of NOTCH1 Mutations in CLL

January 16th 2015

Novel Treatment Approaches to Relapsed/Refractory CLL

January 16th 2015

Strategies for Managing Immune Thrombocytopenia in CLL

January 16th 2015

Maintenance Therapy in Chronic Lymphocytic Leukemia

January 16th 2015

Role of Transplantation in High-Risk CLL

January 16th 2015

Optimizing Treatment With Ibrutinib in High-Risk CLL

January 16th 2015

Safety and Efficacy of Obinutuzumab in CLL

January 16th 2015

First-Line Treatment Selection in CLL

January 16th 2015

Introduction: Upfront Treatment in Patients With CLL

January 16th 2015

FDA Updates Obinutuzumab Frontline CLL Label

December 25th 2014

The FDA has updated the label for obinutuzumab plus chlorambucil to include data from stage 2 of the phase III CLL11 study, which detailed an unprecedented improvement in progression-free survival compared with rituximab plus chlorambucil as a frontline treatment for patients with chronic lymphocytic leukemia.

Frontline Idelalisib Monotherapy Yields High Response Rates in Older Patients With CLL, SLL

December 7th 2014

Idelalisib monotherapy shows activity in treatment-naïve patients ≥65 years with CLL or SLL, with nearly 90% of patients enrolled in a phase II study demonstrating a partial response.

Dr. Jain on the Combination of Idelalisib and Rituximab for Older Patients With CLL

November 26th 2014

Nitin Jain, MD, assistant professor, Department of Leukemia, The University of Texas MD Anderson Cancer Center, discusses the efficacy and safety of the combination of idelalisib and rituximab for older patients with chronic lymphocytic leukemia.

Dr. Brody Discusses Exciting Therapies for Lymphomas and CLL

November 24th 2014

Joshua Brody, MD, assistant professor, Icahn School of Medicine, director, Lymphoma Immunotherapy Program, Mount Sinai Hospital, discusses exciting new therapies for lymphomas and chronic lymphocytic leukemia (CLL).

Juno Files for IPO as CAR Therapies Continue to Advance

November 19th 2014

Juno Therapeutics, Inc, has filed a registration statement for an initial public offering of its common stock, as its early stage therapies continue to advance in clinical trials.

Bringing CARs to Market: Novel T-Cell Therapies Make Rapid Progress Despite Challenges

November 18th 2014

When Marcela V. Maus, MD, PhD, thinks of the challenge of bringing chimeric antigen receptor (CAR) therapies to market in the battle against cancer, she is reminded of the auto industry's first days.

Dr. Jain on Increased Lymphocytosis Following Treatment With a B-Cell Receptor Inhibitor

November 5th 2014

Nitin Jain, MD, assistant professor, Department of Leukemia, The University of Texas MD Anderson Cancer Center, discusses lymphocytosis following treatment with a B-cell receptor inhibitor.

TGR-1202 and Ublituximab Show Promise in CLL

November 5th 2014

As the targeted therapy era in chronic lymphocytic leukemia (CLL) continues to unfold, two next-generation agents are generating responses with improved safety profiles as single agents and in combination regimens