Precision Medicine in Oncology® | Specialty

The OncLive Precision Medicine in Oncology® condition center page is a comprehensive resource for clinical news and expert insights on precision-focused approaches in patients with cancer, with gene-targeted tyrosine kinase inhibitors and antibody-drug conjugates, checkpoint inhibitors, tumor-infiltrating lymphocyte therapy, and other tailored treatments. This page features news articles, interviews in written and video format, and podcasts that focus on updates and ongoing research with personalized therapies across solid and hematologic tumors.

Patient Selection in BRAF-Mutant NSCLC

December 22nd 2016

The Evolving Mutational Landscape in NSCLC

December 22nd 2016

NSCLC: The BRAF/MEK Combination Safety Profile

December 22nd 2016

BRAF/MEK Efficacy in BRAF-mutant NSCLC

December 22nd 2016

Role of the MAP Kinase Pathway in NSCLC

December 22nd 2016

Outcomes With Chemotherapy in BRAF-Mutant NSCLC

December 22nd 2016

Understanding the BRAF-mutated Population in NSCLC

December 22nd 2016

Current Mutation Testing in Lung Cancer

December 22nd 2016

Dr. Dadu on Treatment Approaches in Medullary Thyroid Cancer

December 22nd 2016

Ramona Dadu, MD, assistant professor, Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, discusses treatment approaches in medullary thyroid cancer.

FDA Grants Niraparib Priority Review in Ovarian Cancer

December 20th 2016

The FDA has granted a priority review to a new drug application for the PARP 1/2 inhibitor niraparib for use as a maintenance therapy in patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who have responded to platinum-based chemotherapy.

FDA Approves Rucaparib for Ovarian Cancer

December 19th 2016

The FDA has approved rucaparib (Rubraca) as a treatment for patients with BRCA-positive advanced ovarian cancer who have received at least 2 prior lines of chemotherapy, according to Clovis, the manufacturer of the PARP inhibitor

Mutational Complexity Reflects Treatment Challenges for Hepatocellular Carcinoma

December 19th 2016

The growing incidence of primary liver cancer in the United States poses a great therapeutic challenge.

MSKCC Collaborates With Hackensack Meridian Health in Precision Medicine

December 15th 2016

To great fanfare, Hackensack Meridian Health of New Jersey and Memorial Sloan Kettering Cancer Center announced a co-branding partnership that they say would lead to highly fruitful collaborative research and make hundreds of clinical trial opportunities available to their patients.

President Obama Signs 21st Century Cures Act

December 14th 2016

President Barack Obama signed the 21st Century Cures Act into law today, earmarking $6.3 billion over 10 years for advancements in precision medicine development, brain research, heroin and prescription drug abuse prevention, and mental health.

Dr. Dieras on Combo of Veliparib and Chemotherapy in BRCA1/2-Mutant Breast Cancer

December 13th 2016

Véronique Diéras, MD, Department of Clinical Research, Institut Curie Paris & Saint Cloud, discusses results of a phase II trial exploring the combination of the PARP inhibitor veliparib with chemotherapy in patients with BRCA1/2-mutant breast cancer.

The Future Management of Melanoma

December 9th 2016

Remaining Research Questions in Advanced Melanoma

December 9th 2016

T-VEC Data in the Neoadjuvant Setting in Melanoma

December 9th 2016

Neoadjuvant Trials in High-risk Melanoma

December 9th 2016

Alternative Adjuvant Approaches in Stage III Melanoma

December 9th 2016