Breast Cancer | Specialty

The OncLive Breast Cancer condition center page is a comprehensive resource for clinical news and expert insights on various types of breast cancer, including those that are triple negative, hormone receptor positive, and/or HER2 positive. This page features news articles, interviews in written and video format, and podcasts that focus on treatment advances and ongoing research in breast cancer.

What Is the Role of Maintenance Therapy in Cancer Care?

May 1st 2013

Experts provide an in-depth look at the treatment strategy in patients with solid tumors, specifically looking at the role of maintenance therapy.

Worldwide Effort Yields Major Advances in Identifying Genetic Risks for Breast, Prostate, and Ovarian Cancer

April 30th 2013

A large, international study has yielded a wealth of new information about genetic alterations that can increase an individual's risk of breast, prostate, and ovarian cancer.

Dr. Esserman on Screening Patients With Higher-Risk DCIS

April 30th 2013

Laura Esserman, MD, MBA, Professor, University of California, San Francisco, discusses screening patients with higher-risk DCIS.

Dr. Pegram on Combining Trastuzumab and Pertuzumab

April 26th 2013

Mark D. Pegram, MD, from the Stanford Cancer Institute, describes the combination of pertuzumab and trastuzumab as a treatment for patients with HER2-positive metastatic breast cancer.

Radiotherapy Increases Risk of Heart Disease in Some Women With Breast Cancer

April 26th 2013

While radiotherapy can be an effective treatment for early-stage breast cancer, incidental irradiation of the heart during treatment may increase the risk of developing ischemic heart disease.

Should Sentinel Lymph Node Biopsy Be Postponed Until After Neoadjuvant Therapy?

April 24th 2013

With increasing use of neoadjuvant chemotherapy in early-stage breast cancer, controversy has erupted regarding the optimal timing of sentinel lymph node biopsy.

Dr. Caudle on Upcoming Breast Cancer Trial Results

April 24th 2013

Abigail S. Caudle, MD, Assistant Professor, Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, gives an overview of two trials in breast cancer.

Tumor Biology Is Critical to Making Chemotherapy Choices

April 23rd 2013

The key to advancements in chemotherapy treatment for patients with metastatic breast cancer most likely will come through a better understanding of their underlying tumor biology.

Dr. Chagpar Discusses Surgery for Metastatic Breast Cancer

April 23rd 2013

Anees Chagpar, MD, MSc, MA, MPH, from the Smilow Cancer Hospital at Yale-New Haven, discusses the evolution of surgery as a treatment for patient with metastatic breast cancer.

Dr. Andre Discusses Testing for Genomic Alterations

April 22nd 2013

Fabrice Andre, MD, PhD, from the Institut Gustave Roussy, Villejuif, France, gives an overview of methods for improving the effectiveness of genomic alteration testing in clinical trials that explore novel targeted agents in breast cancer.

Dr. Dixon on Informing a Patient Before Mastectomy

April 19th 2013

J. Michael Dixon, MBChB, MD, discusses the need for physicians to inform patients of the pros and cons before having a mastectomy.

US Supreme Court Hears Arguments in BRCA1/2 Patenting Case

April 18th 2013

The question of whether it should be legal to patent genes has reached the US Supreme Court, and the impending decision by the highest federal court in the country could significantly transform the current research landscape.

Dr. Baselga Discusses Upcoming BOLERO-3 Data

April 18th 2013

José Baselga, MD, PhD, Physician-in-Chief, Memorial Sloan-Kettering Cancer Center, discusses everolimus and the upcoming data from the BOLERO-3 trial in breast cancer.

Use of Personalized Medicine to Select Adjuvant Breast Cancer Therapy

April 17th 2013

Clinical trials are under way that may change the way risk of recurrence is assessed for early-stage breast cancer patients, allowing for individualization of therapy.

Managing Menopausal Symptoms in Breast Cancer Patients

April 16th 2013

J. Michael Dixon, MD, describes a number of effective options for clinicians to help patients better manage menopausal symptoms in patients with breast cancer and improve their quality of life.

Emanuel Petricoin Describes Screening With Biomarkers

April 16th 2013

Emanuel F. Petricoin III, PhD, Co-Director, Center for Applied Proteomics & Molecular Medicine, Professor of Life Sciences, George Mason University, discusses disease screening with biomarkers.

Framing the Mastectomy Debate-The Trends

April 15th 2013

A review of several studies examining the long-term benefits of breast-conservation therapy compared with mastectomy for women with stage breast cancer.

Dr. Sledge Defines the Term "Smart" Cancer

April 15th 2013

George W. Sledge, Jr, MD, Chief, Division of Oncology, Professor of Medicine, Stanford University School of Medicine, defines a "smart" cancer.

Dr. Tripathy on Maintenance Therapy in Breast Cancer

April 12th 2013

Debu Tripathy, MD, co-leader, Women's Cancer Program, University of Southern California Norris Comprehensive Cancer Center, discusses maintenance therapy for patients with breast cancer.

Embracing a Challenge: Breast Cancer Expert Pushes Forward After Much Success

April 12th 2013

An interview with José Baselga, MD, PhD, who helped to develop new drugs and combination therapies for the treatment of breast cancer, including the early targeted therapy trastuzumab and the more recent pertuzumab.