Breast Cancer | Specialty

Dr. Nanda On Pembrolizumab Potential for TNBC

December 12th 2014

Rita Nanda, MD, assistant professor of medicine and associate director of the Breast Medical Oncology Program at the University of Chicago, discusses the potential of pembrolizumab (Keytruda) for the treatment of triple-negative breast cancer (TNBC). A recent small-scale trial showed treatment response for 18.5% of patients with PD-L1 positive TNBC.

Dr. Sikov on Bevacizumab or Carboplatin Impact On TNBC Subtype

December 12th 2014

Dr. Cuzick on Decreasing Breast Cancer Risk With Tamoxifen

December 11th 2014

Chemo Adds No Benefit to Bisphosphonate In Older Breast Cancer Patients

December 11th 2014

Older patients with moderate- or high-risk breast cancer had a similar disease-free survival with the bisphosphonate therapy ibandronate alone or in combination with capecitabine.

Tamoxifen's Sustained Power to Prevent Breast Cancer in High-Risk Women Confirmed

December 11th 2014

Five years of tamoxifen continues to offer protection against breast cancer, reducing the risk of breast cancer by 29% in otherwise healthy women at high risk of the disease who have been followed now for 16 to 22 years.

Ovarian Suppression Emerges as "Practice-Changing" Option for Younger, Premenopausal Breast Cancer Patients

December 11th 2014

Women with HR+ breast cancer who remained premenopausal after receiving chemotherapy had a lower risk of disease recurrence when adding ovarian suppression to adjuvant exemestane or-to a lesser extent-tamoxifen, compared with standard tamoxifen alone, according to results from the phase III SOFT trial.

TNBC Subtype Responds Favorably to Neoadjuvant Bevacizumab

December 11th 2014

The addition of bevacizumab (Avastin) to standard neoadjuvant chemotherapy significantly improved pathologic complete response (pCR) rates in women with basal-like breast cancer compared with non-basal-like subtypes.

Dr. Francis on the Benefits of Ovarian Suppression for Younger Women

December 11th 2014

Nab-Paclitaxel Wins Neoadjuvant Taxane Battle in Breast Cancer Trial

December 11th 2014

Nab-paclitaxel (Abraxane) proved markedly more effective than conventional paclitaxel as part of a neoadjuvant regimen for patients with high-risk early breast cancer in a large German study presented at the 2014 San Antonio Breast Cancer Symposium.

Dr. Weigert on Cancer Screening for Women With Dense Breasts

December 10th 2014

Dr. Edith Perez on Immune Checkpoint Inhibition in TNBC

December 10th 2014

Edith A. Perez, MD, the deputy director at large for the Mayo Clinic Cancer Center, discusses the potential for immune checkpoint blockage as treatment for patients with advanced breast cancer.

Pembrolizumab Elicits Antitumor Responses in TNBC

December 10th 2014

The PD-1 inhibitor pembrolizumab has demonstrated promising clinical activity with an acceptable safety profile in heavily pretreated patients with recurrent metastatic triple-negative breast cancer.

Early Data Find the PI3K Inhibitor Pictilisib Benefits a Subset of Patients With MBC

December 10th 2014

The addition of the investigational PI3K inhibitor pictilisib to fulvestrant in patients with metastatic breast cancer yielded some intriguing findings in the phase II FERGI study.

Chemo Alone May Be Optimal in HER2-Positive Patients With High TIL Levels

December 10th 2014

Among HER2-positive breast cancer patients treated with chemotherapy alone, women with high levels of stromal tumor-infiltrating lymphocytes had an 80% lower likelihood of disease recurrence compared to those with lower TIL counts.

Analyzing CTCs Using Next-Generation Sequencing

December 5th 2014

Next-Generation of CTC Technology

December 5th 2014

Clinical Utility of Circulating Tumor Cells

December 5th 2014

Latest News & Insight: December 5, 2014

December 5th 2014

Joan Lunden to Keynote 32nd Annual Miami Breast Cancer Conference

December 5th 2014

Physicians' Education Resource®, LLC (PER®), to Sponsor Innovative CME Conference for Breast Cancer Specialists

Dr. Carey Discusses Treatment Challenges in TNBC

December 4th 2014

Lisa A. Carey, MD, the Division Chief of Hematology and Oncology at the University of North Carolina and the Physician-in-Chief at North Carolina Cancer Hospital, discusses triple-negative breast cancer (TNBC) and the importance of understanding how it differs from other types of breast cancer.