Brain Cancer | Specialty

The OncLive Brain Cancer condition center page is a comprehensive resource for clinical news and expert insights on various types of brain cancer, including glioma, glioblastoma multiforme, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in brain cancer.


Nivolumab Safe, Effective in Early Stage Glioblastoma Study

June 5th 2016

Single-agent nivolumab demonstrated encouraging signs of activity with a mild adverse event profile for patients with recurrent glioblastoma multiforme.

Temozolomide Trial Shows Improved 5-Year Survival Rates in Anaplastic Glioma

June 4th 2016

Results from a phase III trial investigating the benefit of adjuvant temozolomide in combination with radiation therapy has the potential to be practice changing for a rare type of brain cancer.

Oncolytic Poliovirus Receives Breakthrough Designation for Glioblastoma

May 16th 2016

The recombinant oncolytic poliovirus PVS-RIPO has received breakthrough therapy designation from the FDA as a potential treatment for patients with recurrent glioblastoma multiforme.

Advanced 3D MRI Technology Marks a Leap Forward in Glioblastoma Imaging

May 9th 2016

Although advances have been made in imaging techniques for patients with glioblastoma multiforme, new tools are needed to supplement standard imaging sequences.

Targeted Immunotherapy on Horizon for Brain Tumors

April 6th 2016

The future looks bright for immunotherapies and novel targeted approaches for patients with gliomas, many of which have already been developed for other types of cancer.

Rindopepimut Misses OS Endpoint in Phase III Glioblastoma Trial

March 7th 2016

Treatment with rindopepimut (Rintega) plus temozolomide failed to improve overall survival compared with temozolomide and a control for patients with newly diagnosed EGFRvIII-positive glioblastoma multiforme.

Enhancing Immune System May Boost Survival for Brain Cancer Patients

February 23rd 2016

Researchers at Washington University in St. Louis and elsewhere are focusing on lymphocytes, the essential effector cells in the immune response to cancer.

Novel Treatments in Glioblastoma: Looking Ahead

February 9th 2016

The Optune Device in Glioblastoma: Patient Selection

February 9th 2016

Clinical Experience with Electric Field Therapy in Glioblastoma

February 9th 2016

Treatment Options in Recurrent Glioblastoma

February 9th 2016

Electric Field Therapy in Newly-Diagnosed GBM

February 9th 2016

Systemic Therapy Options in Glioblastoma

February 9th 2016

Goals of Resection in Glioblastoma

February 9th 2016

Multidisciplinary Care in Glioblastoma

February 9th 2016

Diagnostic and Prognostic Markers in Glioblastoma

February 9th 2016

Pathologic Features and Classification of Glioblastoma

February 9th 2016

Progress and Challenges in Glioblastoma

February 9th 2016

Dr. Murphy on Glioma Prognostic Factors in Younger Patients

January 6th 2016

Erin Murphy, MD, associate staff, Department of Radiation Oncology, Cleveland Clinic, discusses a study examining prognostic factors of patients with glioma.

Reardon on Promising Results With Rindopepimut in Brain Cancer

December 30th 2015

David Reardon, MD, discusses the ReACT study and the potential of rindopepimut and other immunotherapy agents for the treatment of patients with brain cancers, specifically glioblastoma.