Christina T. Loguidice

Articles

PARP Inhibitors in Metastatic Castration-Resistant Prostate Cancer: Whom to Treat?

October 28th 2022

PARP inhibitors have emerged as agents that generate improved oncological outcomes in select patient populations with metastatic castration-resistant prostate cancer.

Novel AR-Targeted Therapies for Metastatic Hormone-Sensitive Prostate Cancer: Which One to Choose

October 5th 2022

Advances in the understanding of the genomics and biological functions of prostate cancer have resulted in the emergence of several new classes of agents that have improved outcomes in men with prostate cancer, including metastatic hormone-sensitive prostate cancer.

New JAK Inhibitors and Emerging Novel Agents Expand Myelofibrosis Treatment Arsenal

September 6th 2022

A panel of hematology cancer experts discuss the current treatment landscape and novel emerging therapies for patients with myelofibrosis.

Essential Thrombocythemia and Polycythemia Vera Treatments Are Moving Toward Disease Modification

August 4th 2022

Prevention and mitigation of cardiovascular events, such as thrombohemorrhagic complications, have been the main goal of treatment development for patients with essential thrombocythemia and polycythemia vera.

New Approvals Help Fill Unmet Need in Treating Chronic GVHD

July 26th 2022

A panel of hematology experts discuss use of steroids in the first-line setting as well as several subsequent-line treatments that have recently received FDA approval for patients with steroid-refractory chronic GVHD, which affects up to 50% of patients.

A Growing Arsenal of NSCLC Treatments Take Aim at Oncogenic Fusions

July 5th 2022

A panel of experts discuss their perspectives on testing and targeted therapy for actionable mutations in non–small cell lung cancer.

Combinations Gain Momentum as First-Line Treatments for Unresectable Hepatocellular Carcinoma

May 25th 2022

A panel of hepatobiliary tumor experts discuss several pivotal phase 3 clinical trials examining combination approaches that have expanded or are anticipated to expand the treatment armamentarium for treatment-naïve patients with unresectable hepatocellular carcinoma.

Targeted Treatment Boom Reshapes Differentiated Thyroid Cancer Landscape

April 18th 2022

Marcia S. Brose, MD, PhD, FASCO, and a panel of thyroid cancer experts share their insights into the evolving treatment landscape, including the use of VEGF receptor inhibitors and some of the precision medicine treatments now identified for molecularly selected subsets of patients with differentiated thyroid cancer, such as BRAF, RET, and TRK inhibitors.

Experts Survey Treatment Variations for Resectable NSCLC in Asian Populations

March 25th 2022

A panel of lung cancer experts from China, South Korea, and Japan share their insights on how they care for their patients with resectable EGFR-positive non–small cell lung cancer.

Cervical Cancer Treatment Paradigm Is Bolstered With Newly Approved Therapies

January 28th 2022

Treatment of patients with metastatic cervical cancer remains challenging—the 5-year overall survival rate is just 17%.

Targeted Therapy Innovator Foresees New Paradigms in Breast Cancer

January 26th 2022

Debu Tripathy, MD, discusses key developments that may set the stage for new directions in care of breast cancer, including several areas of the treatment landscape on the cusp of change.

Investigators Navigate the Complicated Treatment Landscape of Chemotherapy-Induced Neutropenia

January 19th 2022

Advances in the treatment of solid tumors and hematologic malignancies have resulted in the development of thera-peutic regimens that can be administered at various points in a patient’s care.

SIMBA Therapy Encounters Barriers But Holds Promise for Neutropenia and Beyond

January 18th 2022

Hope S. Rugo, MD, FASCO, Rita Nanda, MD, William J. Gradishar, MD, and Tiffany A. Traina, MD discuss the selective immunomodulating microtubule-binding agent plinabulin, plus several other novel chemoprotective therapies under exploration, including trilaciclib.

Novel Agents Shake Up Myelodysplastic Syndrome Treatment Landscape

December 27th 2021

During a recent OncLive Peer Exchange®, a panel of hematologic cancer experts shared their insights on the most recent FDA-approved agents for MDS, including luspatercept and decitabine/cedazuridine (Inqovi), both of which were approved in 2020.

Investigators Parse a Crowded Third Line in Relapsed HER2-Positive Metastatic Breast Cancer

December 20th 2021

A panel of breast cancer experts shared their insights on 4 recently approved targeted therapies for patients with relapsed HER2-positive metastatic breast cancer.

Will Slow and Steady Progress in Treating SCLC Win the Race?

October 22nd 2021

Clinical advances in treatment of small cell lung cancer have lagged behind those of other tumor types, but the delay is not for lack of effort.

Frontline Treatments for Metastatic RCC March Forward

September 30th 2021

Treatment of metastatic renal cell carcinoma continues to evolve as new regimens steadily receive FDA approval and are added to the armamentarium.

Precision Medicine Paves the Way for Advances in Hormone Receptor–Positive Breast Cancer

September 29th 2021

Early-stage hormone receptor–positive, HER2-negative breast cancer is generally associated with a good prognosis; however, even with early intervention, some patients recur and have reduced survival.

Novel Combos Target Resistance Mechanisms in Advanced Hormone–Driven Breast Cancer

August 26th 2021

Acquired resistance to endocrine therapy has presented challenges for patients with hormone receptor–positive breast cancer.

NTRK- and RET-Targeted Agents Reshape Solid Tumor Landscape

August 5th 2021

Understanding the oncogenic drivers behind a cancer is taking on increasing importance as more effective agents targeting specific gene aberrations continue to emerge.