Ziftomenib Combined with Venetoclax/Azacitidine in Relapsed/Refractory NPM1-m or KMT2A-r Acute Myeloid Leukemia

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Dr. Amer Zeidan presents interim Phase 1a results from the KOMET-007 trial, demonstrating the safety and robust clinical activity of ziftomenib combined with intensive chemotherapy (7+3) in newly diagnosed adverse-risk NPM1-mutated and KMT2A-rearranged acute myeloid leukemia, highlighting high response rates and promising survival outcomes.

Ziftomenib Combined with Venetoclax/Azacitidine in Relapsed/Refractory NPM1-m or KMT2A-r Acute Myeloid Leukemia: Interim Phase 1a Results from KOMET‑007

I still remember my first time attending the annual American Society of Hematology (ASH) meeting in 2008. I remember feeling completely overwhelmed as I stepped into the enormous convention center, and I remember feeling embarrassingly clueless about which sessions to attend and how to find the rooms where the sessions were being held.

My prior meeting experience was limited to small, oneroom conferences with 100 attendants at the most. This left me unprepared and unsuspecting of how to arrange for these larger meetings. The memories of me getting lost in the hallways during that 2008 meeting ran through my mind as I attended my 6th consecutive ASH meeting this past December in New Orleans.

Plan accommodations early and with colleagues

I see “fellow” fellows share similar experiences while attending major conferences such as the ASH or the American Society of Clinical Oncology (ASCO) annual meetings, where tens of thousands of participants converge. For this reason, I felt that I should share what I have learned about optimizing your experience and making the best use of your time during these meetings.

Once you have decided to attend a meeting, book your hotel as early as possible. Try to book your hotel as soon as the registration opens, as these hotels fill up very quickly. The longer you wait, the higher the likelihood that you will end up in a hotel that is either more expensive or further from the convention center. The same goes for booking your flight. Remember that tens of thousands of people arrive, stay, and leave from where you are traveling at the same time.

Think of the sessions you want to attend before arriving at the convention center

Become familiar with the convention center and locations of presentations

Additionally, ask your colleagues if they are attending the same conference. Sharing a room with a colleague or a friend can be a great way to save money because hotel rooms tend to be very expensive during a major event. The registration websites for the ASH and ASCO conferences tend to have rooms reserved special for conference participants. Booking through these sites can help you receive a more favorable rate; but remember that these rooms go quickly once registration opens.

Look for a list of the activities, lectures, seminars, and poster-viewing sessions that accompany the registration materials that are mailed to you. A calendar of events should also be listed on a conference website. There are also smartphone apps available to facilitate planning a personal itinerary.

During your first day at the convention center, try to orient yourself to the layout of the building. Convention centers tend to be very large and you can get lost easily. Note that some presentations and lecture sessions are held in the hotels that surround a convention center. I suggest researching the location of the hotel in advance if a session of interest to you is being held there. I have missed several sessions in the past that I really wanted to attend due to not studying the map of the convention center and surrounding hotels beforehand and have gotten lost along the way.

Remember to allow time to walk to the activities that you want to attend. There are several simultaneous sessions and lectures and others that are separated by only a few minutes of time. Some are located very far from each other. I have missed the first 10 or 15 minutes of several sessions that I really wanted to attend in the past because I failed to realize how far the rooms were from my current location.

Take advantage of special conference services, particularly those dedicated to fellows Both ASH and ASCO have conference shuttle buses that frequently travel for free between certain hotels and the conference center. Using these buses can save you the cost of a taxi ride or car rental fee, and can spare you the hassle of parking. It also allows you the chance to socialize with fellow participants while traveling. You should inquire at your hotel, or during registration, about travel routes and shuttle times.

Utilize the special services that both ASH and ASCO offer to fellows and members in training 

Both conferences offer special sessions dedicated to fellows that focus on career planning (academic, community, industry, and regulatory settings), discussions of various research pathways (clinical, translational, and basic), explore available funding opportunities and mechanisms, and discuss other subjects of interest to fellows. ASH usually offers a half-day educational session during the first day of the meeting that is dedicated to fellows. This meeting is very useful, but you need to plan to arrive early if attending it.

Additionally, both conferences have a “lounge area” dedicated to fellows and members in training. These lounge areas offer snacks and tea or coffee for free, have useful flyers about fellowship opportunities, offer a quiet setting if you need to prepare for your presentation or send an e-mail, and allow for the opportunity to meet fellows from other states and countries. Remember that these fellows will be your colleagues and possibly research collaborators in the future. You are likely to run into them in the future, so you should take the chance to socialize and network with them.

Submitting an abstract to ASH or ASCO meetings is a very good idea. If your abstract is accepted it will give you the chance to present your research in a very prestigious setting, allow you the chance to meet leaders in your field of research, offer you the chance to improve your presentation skills, and allow you an opportunity to win an “abstract” or “travel” award that can fit very nicely on your CV and offset some of the costs of your trip.

Finally, it is not all about science and medicine. Make sure to leave some time in your itinerary to discover the city where the conference is held. Check out a museum or visit a unique restaurant.

Because we get very busy during fellowship, going out for dinner with friends from your hospital during these conferences can be a good chance to reconnect and catch up, and can help you connect with people in your field.

Amer Zeidan, MD, is a hematology/oncology fellow at the Sidney Kimmel Comprehensive Cancer Center at The Johns Hopkins Hospital in Baltimore, MD.

Articles

I still remember my first time attending the annual
American Society of Hematology meeting in
2008. 

Amer Zeidan, MD

Articles

Ziftomenib Combined with Venetoclax/Azacitidine in Relapsed/Refractory NPM1-m or KMT2A-r Acute Myeloid Leukemia: Interim Phase 1a Results from KOMET‑007

How to Plan for Your Conference Trip