Alice Goodman

Articles

Small Renal Masses in Elderly Can Be Managed by Surveillance

February 14th 2013

Small renal masses identified in elderly patients can be safely managed by surveillance and maintain the same mortality risk as those who undergo surgery, suggesting that surgery could be avoided altogether in many patients.

Shortened Hormone Therapy Course Feasible for High-Risk Prostate Cancer

February 14th 2013

Shortening the course of androgen blockade therapy from 36 months to 18 months when combined with radiation therapy does not appear to compromise outcomes in patients with high-risk prostate cancer

Aggressive Prostate Cancer Risks Higher in Elderly, African-American Men

February 14th 2013

A large, retrospective study has found that high-risk prostate cancer that can only be detected through PSA testing is more likely to occur among men over the age of 75 and in African Americans.

Novel Approach Uses Genomic Analysis to Predict Side Effects of Cancer Treatment

August 24th 2012

A new paradigm that relies on identifying networks or clusters of single nucleotide polymorphisms can accurately predict which patients will develop treatment-related mucositis and other side effects.

Economic Factors Affecting Supportive Care

August 23rd 2012

Research is needed to justify the dollar savings achieved by a supportive care program, but it is not clear what should be measured and how studies should be designed to demonstrate this.

Oncology Nurse Staffing Is Variable and Multifactorial

July 19th 2012

Nurse staffing varies from institution to institution, depending on many factors, both internal and external. To gain a better understanding of nurse staffing, ratios of nurses to patients, and productivity, a survey was sent to ONS members.

Importance of Adequate Nutrition Emphasized

July 17th 2012

Although the role of adequate nutrition in cancer patients is gaining recognition as being important, the area is often neglected as a key component of nursing care.

Considerations in Interpreting Diagnostic Test Results

July 11th 2012

Diagnostic tests are common across the spectrum of cancer care, but results may not always be easily interpreted or applied clinically.

Interventional Radiology: A New Frontier in Cancer Care

July 10th 2012

Nurses involved in cancer care should be up to date on the growing number of applications for interventional radiology in oncology, since some centers may call upon them to work within the quickly developing area.

Diarrhea Less Severe With Molecularly Targeted Agents Than With Standard Chemotherapy

June 30th 2012

Recent evidence shows that some of the newer molecularly targeted therapies can cause diarrhea, which can lead to dose reductions and alterations.

Targeted Therapies Safer for Heart Than Anthracyclines

June 30th 2012

Although molecularly targeted agents can cause cardiac damage, it appears to be reversible and related to cellular dysfunction, as distinct from agents such as anthracyclines that cause cellular death and irreversible cardiac dysfunction.

Brivanib Plus Cetuximab Delivers Mixed Results in Colorectal Study

April 16th 2012

Adding brivanib alaninate to cetuximab had no survival advantage over cetuximab alone in patients with KRAS wild-type chemorefractory metastatic colorectal cancer.

Research Backs Anti-EGFR Therapy in mCRC With Wild-Type KRAS

April 13th 2012

New research on predictive and prognostic biomarkers for therapy targeting EGFR strongly suggests that panitumumab should be reserved for mCRC tumors with wild-type KRAS.

Optical Biomarkers Distinguish Risk Levels in Barrett's Esophagus

April 12th 2012

Optical biomarkers derived from nondysplastic metaplastic cells can detect the presence of high-grade dysplasia and adenocarcinoma from Barrett's esophagus.

Urgent Need for Survivorship Planning

April 10th 2012

Thanks to earlier detection and improved treatment, the population of cancer survivors has increased dramatically and will continue to increase as the baby boomers age.

Bone Microenvironment Promotes Bone Metastases in Prostate Cancer

April 10th 2012

Targeting the bone microenvironment appears to be a potential approach to treating prostate cancer.

Prognostic Factors for Progression of Neuroendocrine Tumors Identified in Reanalysis of RADIANT-2

April 5th 2012

The addition of everolimus to standard octreotide LAR achieved about a 5-month improvement in progression-free survival in patients with advanced neuroendocrine tumors.

Current State of the Art for Treatment of Prostate Cancer

April 3rd 2012

An interview with Nicholas J. Vogelzang, MD, during the ASCO 2012 Genitourinary Cancers Symposium, about treatment of prostate cancer and unmet needs.

Serum-Based Protein Immunoassay Can Detect Early Pancreatic Cancer

April 2nd 2012

An immunoassay to detect the presence of PAM4 showed promise for the detection and diagnosis of early-stage pancreatic ductal adenocarcinoma.

More Research Needed to Define Appropriate Targets for Biologic Therapy of Gastric Cancer

March 30th 2012

More research is needed to define molecular subtypes of gastric cancer and identify appropriate targets for clinical use.